Chief of Staff

Cellular IntelligenceBoston, MA
3dHybrid

About The Position

We are hiring a Chief of Staff who functions as the CEO’s delegate and operating partner. This person increases decision velocity, execution quality, and organizational clarity across a fast-scaling AI x Biology company. You will run the CEO operating system, drive the highest-leverage cross-functional initiatives, and own critical executive communication and fundraising execution. The goal is simple: take a large share of the CEO’s load and reliably turn it into results. Our current Chief of Staff is transitioning into an internal operations role as we scale and will support a thoughtful handoff.

Requirements

  • Off-the-charts excellence: with clear evidence (rapid progression, repeatedly trusted with the hardest problems, exceptional outcomes)
  • High judgment, high ownership: You make good decisions fast, and you finish what you start
  • Structured thinker: You can turn ambiguity into a plan, a set of priorities, and a tight operating rhythm
  • Elite written communication: You can draft CEO- and board-level memos, investor updates, and narratives that are crisp and persuasive
  • Strong executive presence and EQ: You can align scientists, operators, and investors without drama, while holding a high bar
  • Bias to action with high standards: You move quickly without creating chaos or rework
  • Discretion and integrity: Trusted with confidential investor, personnel, and strategic information
  • Travel-ready: Comfortable with a role that may require weekly travel, sometimes on short notice

Nice To Haves

  • Deep tech, AI, or biotech experience, with the ability to learn technical concepts fast and communicate them clearly
  • Prior experience in a high-growth startup environment (0 to 1, 1 to 10, or fundraising-heavy stages)
  • Prior Chief of Staff, GM, or operations leadership experience with direct accountability for outcomes
  • Experience working with boards, investors, and senior executives in high-velocity settings

Responsibilities

  • Build and run the CEO operating system: priorities, weekly planning, meeting architecture, follow-through, and decision logs
  • Own a portfolio of top company initiatives end-to-end: especially cross-functional work spanning science, data, and operations
  • Translate strategy into execution: goals, metrics, resourcing, risk management, and escalation paths that work in real life
  • Represent the CEO with judgment: align leaders, unblock tradeoffs, and drive outcomes with clear guardrails
  • Own executive communication: board cadence, investor updates, key memos, and high-stakes external messaging
  • Drive fundraising execution: narrative, materials, pipeline hygiene, diligence coordination, and post-meeting follow-through
  • Raise organizational throughput: tighten planning, accountability, and hiring and onboarding for critical roles

Benefits

  • A role with real leverage, trust, and scope, not a coordination job
  • Direct partnership with the CEO on the company’s most important decisions and execution
  • Significant exposure to fundraising, strategy, and operating at the leadership level
  • A path to expand into larger leadership roles as the company scales, based on strength and impact
  • Enjoy a competitive salary and benefits package
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