Biophysics Scientist

AmgenThousand Oaks, CA
$110,972 - $150,138

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Biophysics Scientist What you will do Let’s do this. Let’s change the world. In this vital role you will be a member of a team involved in the discovery of innovative biological therapeutics. This team is applying state-of-art experimental technologies that are transforming the way we discover and develop new medicines for our patients.

Requirements

  • Doctorate degree PhD OR PharmD OR MD [and relevant post-doc where applicable] OR Master’s degree and 3 years of scientific experience OR Bachelor’s degree and 5 years of scientific experience

Nice To Haves

  • Knowledge in protein chemistry, cell biology, biophysics, and experience in binding analysis using Surface Plasmon Resonance (SPR).
  • Demonstrated excellent laboratory working ethic and skills, excellent communication skills (both written and oral).
  • Demonstrated flexibility, ingenuity, and problem-solving capability, as well as a strong ability to multi-task.
  • Hands-on experience in lab automation, such as Bravo, Hamilton, biochemical and cellular assays using advanced instruments.
  • Knowledge and hands-on experience in membrane protein generation and characterization are highly desirable.
  • Demonstrated capabilities of bridging experimentation with computational modeling and ML activities.

Responsibilities

  • Using state-of-the-art Surface Plasmon Resonance (SPR) instruments, you will implement and execute high throughput binding affinity characterization on biologics from generative biology, which plays a critical role in Amgen’s drug discovery pipeline.
  • In addition to affinity characterization, you will be expected to determine cross-species selectivity and implement experiments to study mechanism of action when related to binding interactions.
  • You should be meticulous and proficient in generating and analyzing scientific data, and will be expected to communicate the results clearly, both orally and in written form.
  • You will be able to work collaboratively with other scientists, within and across functions.
  • You will be expected to interface with our Computational Sciences Group to develop ML/AI models that improve molecular attributes, such as binding activities.

Benefits

  • A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
  • A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
  • Stock-based long-term incentives
  • Award-winning time-off plans
  • Flexible work models where possible.

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What This Job Offers

Job Type

Full-time

Career Level

Senior

Education Level

Ph.D. or professional degree

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