Associate Scientist, Purification Process

Thermo Fisher Scientific•Wilmington, DE

2d•Onsite

About The Position

Thermo Fisher Scientific is seeking a motivated protein purification scientist to support downstream process development and optimization, primarily for novel therapeutic monoclonal antibody and bispecific products throughout all stages of the clinical lifecycle. The role supports a client through the Laboratories Functional Service Partnership team and is based fully onsite at the customer’s site in Wilmington, Delaware. Applicants from anywhere in the United States are welcome, but relocation assistance is not provided. Candidates must be legally authorized to work in the United States without sponsorship and able to pass a comprehensive background check, including drug screening. The Associate Scientist will develop, optimize, and scale purification processes; conduct protein purification to support formulation material needs and cell culture development; perform routine in-process sample analyses; prepare laboratory buffers and solutions; present weekly work summaries; and maintain routine electronic laboratory notebook entries. The position requires a relevant bachelor’s or master’s degree, with up to two years of relevant industry experience preferred. An equivalent combination of education, training, and directly related experience may be considered.

Requirements

Bachelor’s or master’s degree in biochemistry, bioengineering, biology, chemistry, or a related field.
Basic knowledge of protein chemistry and bioprocessing.
Good verbal and written communication skills.
Ability to work in an organized, collaborative, independent, and meticulous manner.
Must be legally authorized to work in the United States without sponsorship.
Must be able to pass a comprehensive background check, including drug screening.
Able to communicate, receive, and understand information and ideas with diverse groups of people in a comprehensible and reasonable manner.
Able to work upright and stationary and/or standing for typical working hours.
Able to lift and move objects up to 25 pounds.
Able to work in non-traditional work environments.
Able to use and learn standard office equipment and technology with proficiency.
Able to perform successfully under pressure while prioritizing and handling multiple projects or activities.

Nice To Haves

Up to two years of relevant industry experience.
Basic knowledge and preferably hands-on experience with column and membrane chromatography, including affinity, size exclusion, ion exchange, and multi-mode chromatography, as well as filtration technology.
Experience in protein analysis such as HPLC, ELISA, pH, conductivity, and A280 concentration testing.
Hands-on experience or basic knowledge of ultrafiltration/diafiltration experimentation and TFF systems.
Inventory management skills.

Responsibilities

Perform or assist with purification process development, optimization, and scale-up manufacturing.
Conduct protein purification to support the formulation team’s material needs and cell culture development.
Perform routine analyses of in-process samples using relevant product-purity and process-impurity analytical tools.
Prepare buffers and solutions for laboratory work.
Present work summaries at a weekly group meeting.
Write routine electronic laboratory notebook entries.
Perform other responsibilities as assigned.