Associate Director, Site Supply Chain
About The Position
AstraZeneca is seeking an Associate Director, Site Supply Chain for its Cell Therapy Operations, leading end-to-end planning and site operations across manufacturing facilities in Tarzana and Santa Monica, California. Reporting to the Site Supply Chain Director, this role sets and executes site supply chain strategy to support reliable, efficient production and uninterrupted supply of cell therapy products. The position partners with Manufacturing, Quality, Operations, MS&T, and Global Supply Chain to lead the S&OE cadence, optimize capacity and inventory, enable new product introductions, and embed resilient processes and digital tools. The role leads integrated planning for clinical and commercial manufacturing, including demand review, capacity evaluation, production scheduling, site slot management, and finite scheduling. It is accountable for material availability, inventory performance, capacity and utilization planning, supply chain inputs to technical changes and launches, and a monthly S&OE process covering the 0–36-month horizon. The Associate Director also leads and coaches a team, aligns stakeholders, communicates priorities and risks to senior leadership, and uses enterprise and planning systems to turn data into actionable recommendations.
Requirements
- Bachelor’s degree with at least 8 years of experience, or a Master’s degree with at least 6 years of experience, in supply chain, operations, or a related discipline.
- At least 2 years executing site supply chain strategies that improve capacity, inventory levels, production efficiency, service levels, and overall reliability.
- Advanced analytical capability and ability to convert data and scenarios into clear recommendations and plans.
- Demonstrated people leadership and cross-functional influence in GMP manufacturing environments.
- Proficiency with ERP and advanced planning systems, demand planning and slot management tools, and inventory optimization solutions.
Nice To Haves
- Degree in Supply Chain Management, Operations Management, Engineering, Sciences, Business Administration, or a related field; an advanced degree is preferred.
- 10 or more years across supply chain planning, demand forecasting, inventory management, and production planning, ideally in pharma or biotech, with specific experience in cell therapy or advanced therapies.
- Strong knowledge of autologous cell therapy supply chains, including Make-to-Order and Make-to-Stock models, vein-to-vein considerations, and cell therapy capacity planning.
- Experience implementing digital planning capabilities, network modeling, or scenario planning in highly regulated, high-mix/low-volume operations.
- APICS/ASCM or equivalent certification.
Responsibilities
- Lead integrated site planning for Tarzana and Santa Monica clinical and commercial manufacturing, including demand review, capacity evaluation, production scheduling, site slot management, and finite scheduling.
- Optimize resources, cycle time, throughput, and production efficiency while maintaining compliance and quality.
- Ensure timely material availability and deployment through planning, scheduling, replenishment strategies, and actions to prevent supply disruptions.
- Maximize inventory turns while minimizing inventory valuation and scrap.
- Develop and maintain short-, mid-, and long-range capacity scenarios with Site Operations, balancing labor, cleanroom suites, materials, and critical-path steps.
- Own supply chain inputs to technical changes, process improvements, and new product introductions; assess changes, de-risk launches, and maintain continuity through scale-up and tech transfer.
- Set up and lead a monthly S&OE review process to validate the supply plan over a 0–36-month horizon.
- Improve service, inventory, and cost through standard work, process excellence, and digital enablement.
- Implement planning governance, slotting rules, exception management, and tools for S&OE performance and KPI management.
- Lead and coach a high-performing team and align stakeholders across Manufacturing, Quality, MS&T, and Global Supply Chain.
- Communicate priorities, risks, and trade-offs to senior leadership.
- Drive utilization of ERP, demand planning, slotting, and inventory optimization tools, translating complex data into actionable recommendations.
Benefits
- Qualified retirement program (401(k) plan)
- Paid vacation and holidays
- Paid leaves
- Medical, prescription drug, dental, and vision coverage
- Short-term incentive bonus opportunity
- Eligibility to participate in an equity-based long-term incentive program for salaried roles
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What This Job Offers
Job Type
Full-time
Career Level
Senior
