Associate Director, Outcomes Research

Ambry Genetics•Remote - Illinois, IL
•$150,000 - $200,000

About The Position

The Associate Director, Outcomes Research will lead high-impact outcomes research for Tempus’s biopharma partners within the Data Business. This high-visibility, client-facing role combines traditional outcomes research with data science, developing and validating novel epidemiological methods to generate regulatory-grade insights from Tempus’s multimodal datasets and support drug development and patient outcomes. The role oversees retrospective database analyses from study design through execution, serves as a scientific advisor to biopharma clients, and advances innovative real-world evidence methods. It also leads scientific dissemination, partners across Data Science, Biostatistics, Product, Key Account, and Business Development teams, and manages a small team of outcomes research scientists. Research must meet regulatory and ethical standards, including GEP and HIPAA, and be delivered on schedule.

Requirements

  • At least 7 years of experience in HEOR/RWE.
  • At least 3 years of experience in a leadership capacity.
  • Deep expertise in oncology.
  • Proven experience developing or implementing advanced analytical methods, such as target trial emulation, propensity score applications in complex cohorts, causal inference, or machine-learning-augmented epidemiology.
  • Advanced skills in R or SAS.
  • Experience working with real-world data, such as EHR, claims, and/or genomic data.
  • Exceptional ability to explain complex methodological challenges to biopharma executives and translate them into a clear strategic roadmap.
  • Demonstrated experience managing junior scientists.
  • Demonstrated experience leading cross-functional squads in a fast-paced, high-growth environment.

Nice To Haves

  • PhD in Epidemiology, Biostatistics, Health Economics, or a related quantitative field.

Responsibilities

  • Oversee end-to-end execution of retrospective database analyses and architect study protocols that advance HEOR/RWE standards while maintaining scientific rigor.
  • Advise biopharma clients as a subject matter expert on novel, first-in-kind study designs.
  • Contribute to the scientific community through publications and conference presentations, including at ISPOR, ISPE, and ASCO.
  • Partner with Key Account Directors and Business Development to identify opportunities where novel methodology can address client problems, such as rare disease characterization and complex biomarker validation.
  • Lead development of novel real-world evidence methods, including external control arms, causal inference in high-dimensional data, and integration of longitudinal clinical data with molecular and genomic signatures.
  • Set the scientific dissemination strategy and roadmap, and lead authoring and publication of peer-reviewed manuscripts, abstracts, and conference presentations.
  • Bridge Data Science, Biostatistics, and Product teams to productize successful methods and make them scalable across the Tempus ecosystem.
  • Ensure research meets regulatory and ethical standards, including GEP and HIPAA, and deliver high-quality results on time.
  • Manage a small team of outcomes research scientists, providing hands-on project guidance and supporting career development and growth.
  • Lead cross-functional squads in a fast-paced, high-growth environment.

Benefits

  • Incentive compensation may be available, depending on the position.
  • Restricted stock units may be available, depending on the position.
  • Medical and other benefits may be available, depending on the position.
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