Associate Director, Government Pricing

Mirum Pharmaceuticals•Foster City, CA

2d•Hybrid

About The Position

Mirum Pharmaceuticals is a biopharmaceutical company focused on transforming treatment for rare diseases. The Associate Director, Government Pricing is part of the US Payer and Market Access organization and owns the company’s federal and state government price reporting and compliance. The role manages contractual and reporting obligations for programs administered by CMS, the PHS 340B program, the Federal Supply Schedule, and VA and DoD programs. The position leads government pricing calculations, reporting, certifications, and compliance; oversees data integrity and reconciliation; and manages federal contract obligations. It also owns the gross-to-net forecasting process with Finance and Business Analytics, evaluates the impact of commercial and business decisions on government pricing and net revenue, monitors regulatory changes, and supports product launches. The role partners across internal teams and guides the Data Technology Engineering team on related testing and system improvements.

Requirements

6–8 years of experience in Government Pricing and Contract management.
Bachelor’s degree.
Knowledge of U.S. government pricing statutes and regulations, including Medicaid, Medicare, the VA Healthcare Act, and the Public Health Services Act.
Ability to establish and maintain strong working relationships with government representatives at varying levels, including VA Contracting Officers and the Office of Inspector General.
Strong analytical and problem-solving skills.
Attention to detail and a high degree of accuracy to meet timelines and comply with internal policies, laws, and regulations.
Strong Excel and Word skills.
Ability to work independently and take initiative.
Effective written and oral communication skills.
Ability to develop and communicate potential enhancements to operating processes and procedures.
Consistently demonstrate compliance, company values, and required competencies.

Nice To Haves

Involvement in launch preparation or commercialization of a rare disease therapy.
Experience with Inflation Reduction Act compliance, inflation penalties, and CMS inflation rebate modeling.
Experience with government and state pricing transparency calculation and reporting requirements.
Knowledge of class-of-trade strategy, chargeback validation, and specialty distribution models.

Responsibilities

Administer compliance with government-mandated contracting and price administration, including state requirements, pricing calculations, reporting and certifications, trading partner management and eligibility, launch pricing, refunds, and related financial analysis.
Lead calculation, certification, and timely, accurate, compliant submission of government prices, including AMP, Best Price, ASP, URA, 340B, NFAMP, and FCP.
Calculate and submit quarterly PHS prices to HRSA-OPAIS and provisional, temporary, permanent, quarterly, and annual NFAMP/FCP prices to the VA.
Calculate 340B liabilities and refunds resulting from launch pricing or AMP/URA restatements.
Lead state price transparency submissions and analyze results, variances, and key drivers against forecast assumptions.
Maintain government pricing methodologies, assumptions, calculation documentation, and procedures; coordinate and document required government pricing data adjustments.
Support development of policies, procedures, and calculation methodologies for government and state pricing in response to external and internal requirements, including new laws and regulations.
Manage FSS, VA, and DoD contract compliance, including new product pricing submissions, contract maintenance, RFMs, customer monitoring, and Tricare rebate validation.
Lead and perform public law calculations and submissions in coordination with the USMA Payer Account team.
Coordinate five-year FSS solicitations and annual FAR compliance reviews for SAM.gov certification.
Support FSS contracting strategy, including the impact of TPRs, BPAs, and national contracts.
Maintain master data used in government pricing calculations and assess and document adjustments to that data.
Reconcile 3PL and internal transactional data, including sales, chargebacks, credits, fees, and discounts.
Validate chargeback pricing and eligibility and communicate pricing to distribution partners with the Rebates & Chargebacks team.
Work with Trade & Distribution, Accounting, the specialty pharmacy/HUB, and source-system owners to resolve data errors and systemic issues, and document adjustments and validations.
Own GTN forecasting with Finance and Business Analytics, including model maintenance, assumptions, version control, scenario analyses, and routine updates.
Evaluate government pricing and GTN impacts of commercial contracting, pricing, channel strategy, patient support programs, distribution arrangements, and business development initiatives.
Prepare GTN analyses, net revenue impacts, and sensitivities for launch readiness, AOP, LRP, quarterly forecasts, and monthly business reviews.
Develop and maintain government pricing policies, procedures, methodologies, and documentation, and monitor regulatory changes such as the IRA, MFN, and CMS guidance.
Ensure audit readiness and identify and implement process and system improvements across calculations and integrated IT data systems.
Guide the Data Technology Engineering team on related testing.