Vice President, Program Leadership (Launch Products)

Mirum Pharmaceuticals•Foster City, CA

6d•Hybrid

About The Position

The Vice President, Program Leadership (Launch Products) defines and drives global strategy to maximize the long-term value of Mirum Pharmaceuticals’ late-stage and commercial-stage products. The role initially leads strategy across LIVMARLI, ATEBRIOZ, CHOLBAM, and CTEXLI, identifying and prioritizing opportunities to increase patient impact and product value around the world. Acting as the “Program CEO,” the position leads product strategy and execution and brings senior cross-functional leaders together around an integrated product vision. The Program Leader coordinates teams across U.S. and international commercial functions, development, regulatory, medical affairs, CMC/technical operations, market access, finance, legal, and other areas. The role evaluates lifecycle opportunities, makes strategic trade-offs, manages program planning and budgets, and communicates recommendations to executive leadership and governance committees. It also represents the program and Mirum externally with thought leaders, prospective partners, and other stakeholders.

Requirements

15+ years of experience in the biopharmaceutical industry, with significant experience in commercial strategy, marketing, new product planning, global commercialization, or related leadership roles.
Demonstrated success leading global product or lifecycle strategy for marketed and/or late-stage products, including maximizing value across indications, geographies, patient populations, and lifecycle stages.
Strong commercial foundation, including experience in product strategy, positioning, forecasting, market development, launch planning, competitive strategy, and long-range commercial plans.
Global mindset and demonstrated ability to incorporate U.S. and international market needs and perspectives into product strategy and investment decisions.
Significant experience leading senior cross-functional teams across Commercial, Development, Medical Affairs, Regulatory, Market Access, CMC/Technical Operations, Finance, and other functions, including through influence without direct authority.
Ability to operate as an enterprise product leader and integrate commercial, clinical, regulatory, medical, technical, and financial perspectives into a cohesive product strategy.
Strong strategic and financial acumen, including developing business cases, evaluating investment alternatives, understanding product P&Ls and forecasts, and making resource-allocation recommendations.
Track record of effective decision-making amid complexity, uncertainty, competing priorities, and cross-functional trade-offs.
Strong understanding of the global biopharmaceutical commercialization environment, including clinical evidence, regulatory strategy, market access, pricing and reimbursement, competitive dynamics, and commercial execution.
Demonstrated ability to influence and align senior executives and functional leaders, constructively challenge assumptions, resolve differences, and drive teams toward decisions and execution.
Excellent executive communication skills, including synthesizing complex information into clear strategic choices and recommendations for executive leadership and governance bodies.
Strong orientation toward patient impact and value creation, balancing near-term business performance with investments that maximize a product’s long-term potential.
Bachelor’s degree required.

Nice To Haves

Prior experience in rare disease and/or specialty pharmaceuticals.
MBA or other advanced degree.

Responsibilities

Define and execute integrated global lifecycle strategies and long-term value-maximization plans for assigned products, taking account of risks, trade-offs, and value.
Identify and prioritize opportunities across geographies, indications, patient segments, formulations, evidence generation, regulatory pathways, and other lifecycle initiatives.
Reassess product strategy in response to clinical data, competitive developments, market dynamics, regulatory changes, product performance, and intellectual property considerations.
Lead cross-functional Program Teams spanning U.S. and international commercial functions, development, regulatory, medical affairs, CMC/technical operations, market access, finance, legal, and other relevant functions.
Work with regional commercial leaders to assess geographic expansion opportunities and commercialization models, including direct entry, distributors, partnerships, and licensing.
Lead evaluation of new indications, expanded patient populations, label enhancements, combination strategies, and other development opportunities.
Drive cross-functional decision-making and ensure key trade-offs and internal resource constraints are identified, evaluated, and resolved.
Work with Finance and other cross-functional leaders to rationalize, obtain endorsement for, and manage the Program Team budget as part of annual long-range planning.
Develop and communicate business cases, investment recommendations, and strategic scenarios to executive leadership and governance committees to support timely decisions and resource allocation.
Represent the program and Mirum externally with thought leaders, prospective partners, and other stakeholders.
Lead through influence across senior cross-functional stakeholders and create accountability across organizational boundaries.
Translate complex information into clear recommendations and decisions while maintaining a global, long-term perspective and driving near-term execution.