Staff IT Systems Engineer, Endpoints

Lila Sciences • Cambridge, MA

24d • $140,000 - $172,667

About The Position

Lila Sciences is hiring a Staff IT Systems Engineer to own the architecture and roadmap for endpoint management across the company. The position is part of IT & Security and supports laptops, mobile devices, specialized research computing, endpoint security, and device trust. Endpoint management is treated as a software engineering discipline, with configuration, policy, remediation, and fleet operations managed through code, CI/CD, staged rollout, observability, and automated rollback.

This hands-on staff-level role sets technical standards, builds tooling, mentors engineers, and leads cross-functional initiatives across IT, Security, Research Computing, and Lab Operations. The engineer will help make endpoint systems more automated, secure, auditable, and seamless as the company grows, improving employee and scientist productivity while reducing device risk, operational noise, and manual effort.

Requirements

• Deep experience in IT systems engineering, endpoint engineering, infrastructure, or platform engineering, with staff-level technical ownership.
• Strong experience with modern MDM or UEM platforms such as Jamf, Intune, Workspace ONE, or similar tools.
• Experience managing endpoint configuration through code, automation, version control, staged rollout, or CI/CD practices.
• Strong systems knowledge across macOS and Windows endpoint environments.
• Ability to build and maintain automation using Python, Bash, PowerShell, APIs, or similar tooling.
• Experience using AI-assisted engineering, LLM APIs, internal copilots, or agentic automation to reduce operational toil in IT, endpoint, infrastructure, or platform operations.
• Experience partnering with Security on endpoint hardening, device trust, vulnerability management, EDR, or Zero Trust initiatives.
• Strong troubleshooting ability across endpoint, identity, network, application, and user-experience boundaries.
• Track record mentoring engineers, setting technical standards, and leading cross-functional technical initiatives.
• Clear written and verbal communication skills and ability to influence technical decisions across teams.

Nice To Haves

• Experience supporting scientific, research, lab, OT, or high-performance computing environments.
• Familiarity with Okta, SAML, SCIM, device trust, SASE, EDR, or cloud access patterns.
• Experience with AWS, GCP, cloud-native infrastructure, or cloud-based endpoint telemetry workflows.
• Experience with open-source endpoint tooling such as osquery, Fleet, Munki, or similar tools.
• Experience building VDI, managed browser, call center, or contact center computing environments.
• Proficiency in Go, Swift, or another language used for custom endpoint tooling.
• Experience in a regulated, IP-sensitive, biotech, life-sciences, or research environment.

Responsibilities

• Own the architecture and roadmap for the endpoint fleet across macOS, Windows, Linux, mobile devices, and specialized research or lab computing endpoints.
• Define standards for endpoint configuration, policy, remediation, observability, and rollout practices across IT & Security.
• Drive configuration-as-code adoption for MDM policies, profiles, scripts, staged rollouts, canary groups, and automated rollback.
• Design zero-touch provisioning workflows so devices arrive encrypted, configured, compliant, and ready for use.
• Partner with Security to integrate endpoint posture, device trust, vulnerability data, EDR, and Zero Trust access controls.
• Build automation and internal tooling using scripts, APIs, CI/CD, and AI-assisted engineering practices to reduce manual toil.
• Improve vulnerability and patch management through telemetry, dashboards, drift detection, and auditable compliance workflows.
• Support specialized computing environments, including research workstations, lab-adjacent systems, VDI, managed browsers, and remote-access patterns where appropriate.
• Serve as a technical escalation point for complex endpoint issues and mentor engineers across IT and Security.
• Partner with Security, Legal, HR, Research Computing, and Lab Operations to protect sensitive IP while keeping the employee experience seamless.

Benefits

• Competitive base compensation with bonus potential and generous early-stage equity.
• U.S. full-time employees receive medical, dental, and vision coverage.
• Employer-paid life and disability insurance for U.S. full-time employees.
• Flexible time off and generous company-wide holidays for U.S. full-time employees.
• Paid parental leave for U.S. full-time employees.
• Educational assistance program for U.S. full-time employees.
• Commuter benefits, including bike-share memberships for office-based employees.
• Company-subsidized lunch program for U.S. full-time employees.
• Regionally tailored comprehensive benefits for full-time employees outside the U.S.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: No Education Listed