Sr. Scientist - Mass Spec Production (LC-MS/MS)

KCAS Bio • Kansas City, MO

9d

About The Position

The Sr. Scientist in the Mass Spec Bioanalysis Production group is responsible for carrying out all aspects of regulated bioanalytical studies, from study setup through reporting. The role applies scientific principles and regulatory expectations to protect data integrity, troubleshoot issues, and deliver high-quality results in a GLP-compliant environment. The group uses LC-MS/MS techniques and sophisticated sample preparation methods to support drug discovery, preclinical, and clinical studies, including analysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues.

Requirements

• Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, or a related field.
• At least 5 years of experience in a bioanalytical laboratory environment.
• Extensive hands-on experience in a GLP-regulated laboratory environment.
• Strong experience with bioanalytical sample preparation and quantitative LC-MS/MS workflows.
• Experience executing regulated studies, including data review, reporting, and audit support.
• Demonstrated ability to troubleshoot technical and operational issues in a production environment.
• Experience interacting with Quality Assurance and supporting audits and inspections.

Nice To Haves

• Prior experience acting as a study lead or in a Principal Investigator-type role.

Responsibilities

• Execute and oversee all phases of assigned studies, including sample preparation, LC-MS/MS analysis, data review, and report generation in a regulated environment.
• Act as lead scientist on studies, providing work direction, technical guidance, and training to junior scientific staff.
• Handle client communication related to study conduct and data delivery.
• Interact with Quality Assurance to resolve audit findings, deviations, and compliance-related issues.
• Make final decisions on sample identification, including resolving discrepancies with clinical sites and clients.
• Manage study timelines and deliverables, and communicate status to management and clients.
• Ensure study activities comply with study protocols, SOPs, and GLP regulatory requirements.
• Review data for accuracy, completeness, and integrity before reporting.
• Support audit readiness and participate in client and regulatory inspections as needed.
• Troubleshoot assay performance and operational challenges in a production environment.
• Perform duties in a manner that supports the company’s brand, mission, vision, and values.

Benefits

• Company-sponsored events, including food trucks, family days, and spirit days.
• Career development through KCAS University.
• Employee groups and opportunities to connect around wellness, inclusion, and community outreach.
• Stock ownership program.
• Access to the latest technology.
• Paid time off to volunteer.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior