Scientist III - Mass Spec Production (LC-MS/MS)
About The Position
The Scientist III in the Mass Spec Bioanalysis Development group performs and takes ownership of significant study activities, from study setup through reporting, and contributes to development work. The role applies bioanalytical and scientific principles to execute studies, assess data integrity, and troubleshoot issues. The team uses LC-MS/MS techniques and sophisticated sample preparation methods to support drug discovery, preclinical, and clinical studies, including analysis of drugs and metabolites, biomarkers, and active endogenous compounds in biological fluids and tissues. The position also contributes to method development, qualification, and optimization, interprets data with minimal oversight, prepares data summaries, and supports report generation. Study work must comply with applicable study protocols, SOPs, and regulatory requirements. The Scientist communicates study progress to senior scientists and management and guides junior scientific staff. Depending on a candidate’s background and qualifications, KCAS Bio may consider them for one of three Scientist levels, as determined during the interview process.
Requirements
- Bachelor’s, Master’s, or PhD in Chemistry, Biochemistry, chemical or biochemical engineering, or a related field.
- At least 4–6 years of experience with LC-MS/MS.
- Strong experience with bioanalytical sample preparation, quantitative LC-MS/MS, and multi-dimensional chromatography.
- Experience contributing to method development, qualification, and complex troubleshooting.
- Experience working in a regulated environment (GLP/GxP).
Nice To Haves
- Experience with proteins and peptides as well as small molecule biomarkers.
- Experience with reversed phase and HILIC chromatography at analytical flow rates, or protein digestions and immunoaffinity enrichments (hybrid LCMS).
Responsibilities
- Execute and take ownership of key study components, including sample preparation, LC-MS/MS analysis, troubleshooting, data analysis, and documentation.
- Contribute to method development, qualification, and optimization efforts.
- Troubleshoot complex technical issues and recommend solutions.
- Analyze and interpret data with minimal oversight.
- Prepare data summaries and contribute to report generation.
- Ensure study activities comply with applicable portions of study protocols, SOPs, and regulatory requirements.
- Communicate study progress to senior scientists and management as required.
- Provide guidance and mentorship to junior scientific staff.
- Perform job duties in a manner that supports the company’s brand, mission, vision, and values.
- Perform additional duties as requested.
Benefits
- Company-sponsored events, including food trucks, family days, and spirit days.
- Career development through KCAS University.
- Stock ownership program.
- Access to the latest technology.
- Paid time off to volunteer.
- Wellness, inclusion, and community outreach opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
