Sr. Manager, Scientific Product Management

Addgene•Watertown, MA

6d•$130,000 - $155,000•Hybrid

About The Position

Plasmids are Addgene’s largest and most established product portfolio. They are also the platform from which everything else grows — viral vectors, antibodies, new formats, new markets. The Senior Manager, Scientific Product Management owns day-to-day execution across this portfolio, which includes segmentation, catalog health, roadmap delivery, and launch execution, in close partnership with the Director of Scientific Product Management. This is a role for someone who wants to grow a business — who leads with outcomes, moves with urgency, and knows how to translate scientific insight into commercial results. The right candidate will inherit a portfolio with strong foundations and significant untapped potential, and will be expected to deliver on both in the near term while building the strategic runway for 2028 and beyond. To Succeed in this Role, You Will Own: Portfolio Performance & Analytics Track and report on plasmid portfolio performance — including revenue growth, margin optimization, and long-term portfolio health — and deliver on targets set in the Annual Operating Plan (AOP). Set and hit clear performance targets for the portfolio: revenue growth, adoption rates, market penetration, and customer retention across academic, biotech, and pharma segments. Identify performance gaps and recommend pricing, positioning, promotional, or product-mix adjustments to protect and grow commercial outcomes. Product Strategy & Roadmap Execution Execute the multi-year plasmid product roadmap, balancing near-term revenue delivery with longer-term innovation bets. Drive the full product lifecycle for the plasmid portfolio — from opportunity identification and concept validation through launch, growth, optimization, and, where appropriate, rationalization. Support the I2L (Idea-to-Launch) pipeline for plasmid-related innovations, including new formats like Transfection-Ready DNA, defining what comes next on that roadmap, and shepherding line extension projects through gate decisions. Apply plasmid segmentation outputs to prioritize where Addgene invests, where it defends, and where it rationalizes — making clear, defensible calls with supporting data. Develop and implement a plasmid intake evaluation framework for large deposits, including accept/decline criteria and cost-benefit analysis, to improve catalog quality and scalability. Market Insight & Commercial Intelligence Run an ongoing Voice of the Customer (VOC) program, translating researcher needs into product priorities and roadmap recommendations. Maintain deep knowledge of the plasmid competitive landscape — who the players are, what they offer, how Addgene is positioned, and where the gaps and white space lie. Monitor market trends, funding shifts, and emerging research applications (e.g., gene therapy, synthetic biology, CRISPR) to anticipate demand and position the portfolio ahead of the curve. Turn market intelligence into concrete recommendations, pricing moves, product concepts, or go-to-market adjustments. Go-to-Market Execution Execute annual commercial plans for the plasmid portfolio — launch activities, marketing coordination, channel activation, and partnership initiatives — in partnership with Marketing, Distribution, and Business Development. Own the commercial launch of Transfection-Ready DNA and any subsequent new formats, from go-to-market strategy through post-launch performance monitoring and optimization. Define clear value propositions and messaging for each plasmid segment, ensuring Addgene’s positioning is differentiated, credible, and compelling to target customers. Partner with the Distribution Manager to ensure distributor partners are equipped, motivated, and accountable for plasmid sell-through in their markets. 2027 Planning & Strategic Roadmap Provide plasmid portfolio analysis and input into the 2027 Operating Plan and 3–5 year commercial roadmap, under the Head of Product Management's direction. Develop business cases and Market Requirements Documents (MRDs) for new product ideas advancing through the I2L process, ensuring each is grounded in customer evidence and commercial viability. Surface partnership opportunities that could accelerate plasmid portfolio growth for the Business Development team to evaluate. Cross-Functional Leadership Lead cross-functional core teams — spanning Operation, R&D, Marketing, Scientific Engagement, Operations, and Digital product— to deliver portfolio objectives on time and to commercial standard. Hold cross-functional partners accountable to shared milestones and commercial outcomes, escalating blockers quickly and decisively. Serve as the internal authority on the plasmid portfolio — the person who knows it best, advocates for it most effectively, and can represent it credibly to any audience. Represent Addgene externally at conferences, partner meetings, and industry events, building market presence and returning with actionable intelligence.

Requirements

Bachelor’s degree in a life sciences discipline; advanced degree (PhD or master’s in molecular biology, biochemistry, genetics, or related field) strongly preferred and carries significant weight.
5–7 years of progressive commercial experience in the life sciences sector, including experience in product management, portfolio execution, or a directly adjacent commercial role.
Demonstrated track record of owning a product portfolio P&L and delivering revenue growth and margin improvement
Deep understanding of discovery researcher needs, workflows, and purchasing behavior in academic and industry settings, with the ability to translate that understanding into commercial strategy.
Proven experience leading products through a structured innovation or stage-gate process (I2L, Phase-Gate, or equivalent) from concept through commercial launch.
Strong analytical and financial acumen: comfortable building business cases, interpreting performance data, and making data-driven recommendations
Demonstrated ability to lead and influence cross-functional teams without direct authority, and to hold peers accountable to shared commercial goals.
Excellent communication skills — able to present to executive leadership, engage credibly with scientists, and align commercial teams around a clear strategy.
Commercially oriented mindset: you measure success by outcomes, not outputs.

Nice To Haves

Direct experience with plasmid biology, molecular cloning, or related reagent formats (viral vectors, CRISPR tools); hands-on laboratory experience is a genuine plus.
Experience in a nonprofit, CRO, or mission-driven life science organisation where commercial goals must be balanced with broader values.
Familiarity with Addgene’s portfolio, repository model, or academic distribution channels.
Experience developing or applying VOC methodologies and customer segmentation frameworks in a life science product context.
Track record of building productive working relationships with marketing, channel, and BD counterparts to drive integrated go-to-market execution.

Responsibilities

Track and report on plasmid portfolio performance — including revenue growth, margin optimization, and long-term portfolio health — and deliver on targets set in the Annual Operating Plan (AOP).
Set and hit clear performance targets for the portfolio: revenue growth, adoption rates, market penetration, and customer retention across academic, biotech, and pharma segments.
Identify performance gaps and recommend pricing, positioning, promotional, or product-mix adjustments to protect and grow commercial outcomes.
Execute the multi-year plasmid product roadmap, balancing near-term revenue delivery with longer-term innovation bets.
Drive the full product lifecycle for the plasmid portfolio — from opportunity identification and concept validation through launch, growth, optimization, and, where appropriate, rationalization.
Support the I2L (Idea-to-Launch) pipeline for plasmid-related innovations, including new formats like Transfection-Ready DNA, defining what comes next on that roadmap, and shepherding line extension projects through gate decisions.
Apply plasmid segmentation outputs to prioritize where Addgene invests, where it defends, and where it rationalizes — making clear, defensible calls with supporting data.
Develop and implement a plasmid intake evaluation framework for large deposits, including accept/decline criteria and cost-benefit analysis, to improve catalog quality and scalability.
Run an ongoing Voice of the Customer (VOC) program, translating researcher needs into product priorities and roadmap recommendations.
Maintain deep knowledge of the plasmid competitive landscape — who the players are, what they offer, how Addgene is positioned, and where the gaps and white space lie.
Monitor market trends, funding shifts, and emerging research applications (e.g., gene therapy, synthetic biology, CRISPR) to anticipate demand and position the portfolio ahead of the curve.
Turn market intelligence into concrete recommendations, pricing moves, product concepts, or go-to-market adjustments.
Execute annual commercial plans for the plasmid portfolio — launch activities, marketing coordination, channel activation, and partnership initiatives — in partnership with Marketing, Distribution, and Business Development.
Own the commercial launch of Transfection-Ready DNA and any subsequent new formats, from go-to-market strategy through post-launch performance monitoring and optimization.
Define clear value propositions and messaging for each plasmid segment, ensuring Addgene’s positioning is differentiated, credible, and compelling to target customers.
Partner with the Distribution Manager to ensure distributor partners are equipped, motivated, and accountable for plasmid sell-through in their markets.
Provide plasmid portfolio analysis and input into the 2027 Operating Plan and 3–5 year commercial roadmap, under the Head of Product Management's direction.
Develop business cases and Market Requirements Documents (MRDs) for new product ideas advancing through the I2L process, ensuring each is grounded in customer evidence and commercial viability.
Surface partnership opportunities that could accelerate plasmid portfolio growth for the Business Development team to evaluate.
Lead cross-functional core teams — spanning Operation, R&D, Marketing, Scientific Engagement, Operations, and Digital product— to deliver portfolio objectives on time and to commercial standard.
Hold cross-functional partners accountable to shared milestones and commercial outcomes, escalating blockers quickly and decisively.
Serve as the internal authority on the plasmid portfolio — the person who knows it best, advocates for it most effectively, and can represent it credibly to any audience.
Represent Addgene externally at conferences, partner meetings, and industry events, building market presence and returning with actionable intelligence.

Benefits

85% company-paid healthcare premiums including dental (extending to family members) and 100% company-paid deductible
Life, short-term, and long-term disability insurance.
22 days of PTO on top of our winter break closure and company holidays.
A 403(b) retirement account with a company match of 4% after 2 years of employment.
Annual professional development stipend
Annual lifestyle stipend
Fully paid public transportation for employees who work onsite two or more days per week.
Onsite yoga classes & wellness reimbursement
Pet insurance
Annual financial planning one-on-ones with our plan administrator