Sr. Director, MASH/ALD Brand Lead & Pipeline

GSK•Durham, DC

12d

About The Position

The role serves as commercial Brand Lead for MASH/ALD assets and the primary U.S. commercial authority for the broader Hepatology/Immunology pipeline and portfolio. It has end-to-end accountability for pipeline strategy from early development through launch readiness and lifecycle management. The role shapes commercial strategy for MASH/ALD assets as they progress toward potential commercialization and sets the commercial vision and strategic framework for investment decisions, stage-gate recommendations, and commercialization planning across the broader portfolio. It represents the U.S. customer and commercial perspective in governance forums and global decisions. The role builds the commercial foundation for pipeline assets before dedicated brand teams are established, including positioning hypotheses, customer segmentation frameworks, and go-to-market approaches. For MASH/ALD, it leads commercial strategy today and is expected to evolve into the full Brand Lead role as the asset advances through development and, if approved, toward launch. Leadership scope is expected to expand as commercialization planning, launch readiness, and cross-functional leadership needs increase. The position leads U.S. portfolio and lifecycle strategy, market and competitive assessments, stage-gate recommendations, portfolio prioritization, and early payer and value-positioning work. It partners with U.S. and global commercial, medical, market access, finance, forecasting, research, and business development stakeholders. It also manages pipeline and portfolio strategy budgets, supports financial assumptions and launch outlooks, and provides strategic leadership and talent development across the Hepatology/Immunology commercial organization.

Requirements

Bachelor's degree in Marketing, Business, Life Sciences, or a related field.
At least 10 years of experience in pharmaceutical, biotech, or healthcare roles, with Hepatology/Immunology experience in at least one relevant function.
In-line brand marketing or brand management experience, ideally as a Brand Lead in specialty pharmaceutical or biotech, with direct accountability for brand strategy, positioning, customer segmentation, or launch planning for HCP-facing specialty assets.
Experience with HCP- or patient-administered specialty medicines.
Experience owning commercial strategy for pipeline and/or in-line assets.
Experience leading cross-functional portfolio and/or pipeline initiatives.
Experience leading strategic discussions with executive leadership based on data-driven commercial insights.
Experience managing budgets and investment priorities across a program or multi-asset portfolio.
Direct people leadership experience and a track record of developing talent and building high-performing teams.
Willingness to relocate to Durham, North Carolina.

Nice To Haves

Advanced degree, such as an MBA, master's degree, or equivalent.
Demonstrated Hepatology/Immunology marketplace experience, including deep understanding of patients, customers, competitors, and business drivers across relevant specialties.
Demonstrated leadership in portfolio, pipeline, or new product strategy, including leading assessments of go-to-market models and P&L optimization initiatives.

Responsibilities

Serve as the commercial and Brand Lead for MASH/ALD assets, shaping commercial strategy and leading cross-functional planning and launch-readiness activities.
Own U.S. pipeline and portfolio strategy for Hepatology/Immunology assets, including commercial vision and prioritization from Phase 2 through LOC activation.
Develop U.S. market analyses, competitive assessments, and commercial assumptions with the Medicines Commercialization Team and Integrated Brand Commercialization Teams.
Represent U.S. HCP, patient, and payer perspectives in early development decisions and serve as the accountable U.S. commercial input at early stage-gates.
Build the pre-launch commercial foundation for priority assets, including input to target product profiles, positioning hypotheses, customer segmentation, and initial value propositions.
Deliver recommendations for Phase 2, 2b, and 3 stage-gate decisions, articulating U.S. opportunity, risk, and go/no-go rationale.
Establish and evolve a long-range Hepatology/Immunology portfolio vision, including asset prioritization, sequencing, and strategic planning.
Lead U.S. portfolio and lifecycle strategy across in-line and pipeline assets, informing resource allocation and investment choices.
Develop market maps and portfolio strategies that account for customer and patient needs, financial impacts, the healthcare landscape, specialties, indications, and lifecycle opportunities.
Translate market and environmental assessments, brand performance, customer experience, expert input, competitive trends, reimbursement trends, and market access dynamics into forward-looking strategy.
Maintain expertise in brand narratives, disease landscapes, competitive dynamics, and customer segments for priority assets.
Partner with U.S. Health Outcomes, Medical Affairs, and Market Access on clinical, health outcomes, economic evidence, brand value positioning, and early payer strategy.
Evaluate go-to-market models, customer engagement, channel strategies, and P&L optimization opportunities.
Serve as the primary U.S. commercial authority at global governance forums, including FRC, PIB, and relevant stage-gate committees.
Act as a delegated U.S. commercial decision-maker and strategic advisor to the Marketing VP on pipeline and portfolio decisions.
Build relationships with strategy and business unit leadership and provide commercially grounded assessments of relevant business development opportunities.
Own the pipeline and portfolio strategy budget, including market research, competitive intelligence, and pipeline analytics, and prioritize investment and resources.
Collaborate with Forecasting & Finance on launch outlooks, financial assumptions for pipeline assets, and portfolio value opportunities.
Provide strategic leadership across pipeline strategy and early commercialization, setting direction and high standards for cross-functional teams.
Contribute to succession planning, talent development, and organizational health across the Hepatology/Immunology commercial organization.
Collaborate with U.S. business units, Global Therapy Areas, Therapy Area Research Leaders, Medical Development Leads, Forecasting & Finance, Health Outcomes, and Business Development on priorities and enterprise decisions.
Lead cross-functional commercial planning for MASH/ALD and work with Brand Leads, Medical Affairs, Market Access, Commercial Leadership, Sales, Insights & Analytics, Finance, Medical, and Global Product Strategy.