Flagship Labs 111: Small Molecule Drug Discovery Co-Op

Flagship Pioneering•Cambridge, MA

1d•Onsite

About The Position

This position is open exclusively to current Northeastern University Co-Op students. Work Period: January 2027 to June 2027. This is a full - time, 40 hours per week position with 5 days in office. Flagship Labs 111 Inc. (FL111) is a privately held, early-stage biotechnology company pioneering a novel platform harnessing innovations in chemistry, computation, and data science to create new therapeutic modalities beyond traditional small molecules. FL111 is backed by Flagship Pioneering, bringing the courage, vision, and resources to guide FL111 from platform validation to patient impact. We are seeking collaborative, creative and relentless problem solvers that share our passion for impact to join us! Flagship Labs 111 is a product of Flagship Pioneering's venture creation engine that invents and builds platform companies, each with the potential for multiple products that transform human health or sustainability. Since its launch in 2000, Flagship has originated and fostered more than 100 scientific ventures, resulting in more than $90 billion in aggregate value. Many of the company’s Flagship has founded have addressed humanity’s most urgent challenges: vaccinating billions of people against COVID-19, curing intractable diseases, improving human health, preempting illness, and feeding the world by improving the resiliency and sustainability of agriculture. Flagship has been recognized twice on FORTUNE’s “Change the World” list, an annual ranking of companies that have made a positive social and environmental impact through activities that are part of their core business strategies and has been twice named to Fast Company’s annual list of the World’s Most Innovative Companies. Learn more about Flagship at www.flagshippioneering.com. Flagship Pioneering Co-Op Program Welcome to Flagship Pioneering Co-Op Program for the cohort dreaming big and taking courageous leaps. You'll join fellow peers across our ecosystem of companies and learning firsthand how we build first-in-category companies. You’ll have access to enrichment sessions, a dedicated professional development track, and a mentor that help guide you toward your next step. By the end, you will carry on a meaningful project outcome, a genuine network, and a front-row view of how Flagship pioneer new ventures that change the world. We're looking for an enthusiastic co-op student eager to learn the laboratory skills used in small molecule drug discovery. You will set up, run, and analyze biochemical and cell-based assays for the screening and characterization of small molecules in cancer biology.

Requirements

Currently pursuing an undergraduate degree in Biology, Biochemistry, Chemistry, Biomedical Sciences, or a related field.
No prior co-op or industry lab experience required — this role is designed to build foundational skills.
Willingness and enthusiasm to learn hands-on laboratory technique.
Basic familiarity with lab safety practices and general chemistry/biology coursework.
Strong attention to detail and willingness to follow written protocols precisely.
Good organizational habits and clear written/verbal communication.
Ability to work collaboratively in a team lab environment.

Nice To Haves

Coursework or lab exposure to cell culture, biochemistry, or molecular biology techniques.
Familiarity with Excel; exposure to GraphPad Prism a plus.
Interest in oncology or small molecule drug discovery.

Responsibilities

Culture and maintain cancer cell lines for assay use.
Prepare compound plates via reconstitution and serial dilution.
Run luminescence and fluorescence assays on plate readers.
Perform Western blot analysis for protein detection.
Analyze and present data using Excel, GraphPad Prism, and PowerPoint.
Maintain accurate, complete records in an electronic lab notebook (ELN).
Communicate results within the FL111 team and collaborate with other Flagship companies as needed.