Sequencing Process Development Specialist

Eurofins•Louisville, KY

1d•Hybrid

About The Position

We are seeking an experienced, highly capable, and detail-oriented Sequencing Process Development Specialist to join our production laboratory team in a hybrid role supporting both Sanger sequencing and Oxford Nanopore Technologies (ONT) workflows. This position is intended for a senior-level technical contributor who combines strong bench execution with leadership in process improvement, troubleshooting, training, compliance, and cross-functional technical support. The Sequencing Process Development Specialist will play a key role in daily production while also serving as a subject matter resource for sequencing operations. This individual will be expected to contribute meaningfully to R&D initiatives, workflow optimization, assay and process improvement, training of team members, investigation of technical issues, and support of documentation and compliance expectations. In addition to hands-on bench responsibilities, this role will partner closely with laboratory leadership and internal support teams to improve quality, throughput, robustness, and customer support outcomes. This position is best suited for someone with a strong molecular biology and sequencing background who is comfortable working in a fast-paced, high-throughput environment and can operate with a high level of independence, technical judgment, and accountability.

Requirements

Bachelor’s degree in Biology, Molecular Biology, Biochemistry, Genetics, Biotechnology, Chemistry, or a related scientific field; advanced degree preferred.
Significant directly relevant laboratory experience in DNA sequencing, genomics, or molecular biology production workflows.
Demonstrated experience performing hands-on sequencing-related bench work in a production, development, or applied laboratory environment.
Ability to work independently, prioritize effectively, and make sound technical decisions within established workflows.
Strong written and verbal communication skills, with the ability to train others and interact effectively with cross-functional teams.
Ability to follow written procedures, maintain accurate documentation, and comply with established quality systems and company policies.
Authorization to work in the United States indefinitely without restriction or sponsorship.
Strong technical knowledge of sequencing workflows and molecular biology laboratory practices.
Strong troubleshooting skills and ability to identify root causes of workflow, assay, or instrument issues.
Ability to recognize inefficiencies and recommend practical process improvements.
Strong training and mentoring capability, with patience and clarity in technical communication.
High level of attention to detail and commitment to quality, compliance, and data integrity.
Ability to work effectively under production deadlines without compromising accuracy.
Strong organizational skills and ability to manage multiple priorities simultaneously.
Professional judgment, initiative, and accountability appropriate for a senior technician role.
Positive, collaborative attitude and willingness to support team success across both routine production and special projects.

Nice To Haves

Direct experience with both Sanger sequencing and next-generation sequencing workflows; ONT experience strongly preferred.
Experience operating ABI 3730xl instrumentation.
Experience with library preparation, sequencing QC, troubleshooting, and production support in high-throughput laboratory environments.
Experience with automation platforms, liquid handlers, or process standardization efforts.
Experience supporting assay development, validation, workflow optimization, or R&D activities.
Experience training peers or serving as a technical lead, senior technician, or subject matter resource.
Familiarity with sequencing data review, quality metrics, and basic interpretation of run performance.
Experience working in regulated or quality-driven environments such as GLP, GMP, cGMP, ISO, or similar systems.
Familiarity with LIMS, controlled documentation, deviation follow-up, and data integrity expectations.
Exposure to molecular biology methods such as PCR, qPCR, dPCR, nucleic acid extraction, library QC, quantification, and purification workflows.

Responsibilities

Perform hands-on laboratory work in support of daily Sanger sequencing and ONT sequencing production workflows.
Organize, prioritize, and process incoming DNA samples according to daily production needs and turnaround expectations.
Prepare sequencing reactions, perform purification steps, and execute required pre- and post-run workflow tasks for Sanger sequencing.
Prepare ONT libraries using established protocols while maintaining strong attention to quality, consistency, and throughput.
Load, operate, schedule, and monitor sequencing instrumentation, including ABI 3730xl sequencers and Oxford Nanopore sequencing platforms.
Operate standard laboratory instrumentation such as thermocyclers, centrifuges, liquid handlers, quantification systems, and QC instruments.
Troubleshoot routine and non-routine workflow issues, sequencing failures, and instrument-related concerns; escalate appropriately and help drive resolution.
Serve as a technical resource to team members by answering workflow questions, supporting investigations, and assisting with training and onboarding.
Train other technicians on sequencing workflows, laboratory best practices, documentation expectations, troubleshooting approaches, and quality-focused execution.
Support and participate in R&D activities, workflow development, proof-of-concept studies, validation work, and implementation of improved methods.
Identify opportunities for process improvement, automation, standardization, and error reduction across sequencing operations.
Work with internal support groups such as quality, IT/LIMS, bioinformatics, customer support, and laboratory leadership to address technical questions and improve workflow performance.
Assist with technical review of sequencing performance, QC trends, and operational issues to help maintain quality and turnaround time goals.
Support compliance by following controlled documents, maintaining accurate batch records and production logs, and reinforcing data integrity and documentation practices.
Assist in drafting, revising, or improving work instructions, checklists, training materials, and other operational documentation as needed.
Contribute to root cause investigations, corrective actions, and implementation of preventive measures when quality or process issues arise.
Maintain strong communication with supervisors, team leads, and cross-functional stakeholders regarding production status, technical issues, and improvement opportunities.