Senior Software Engineers

The businesses of Merck KGaA, Darmstadt, Germany•St. Louis, MO

13h•$147,000 - $157,000•Hybrid

About The Position

Sigma-Aldrich Corporation is hiring Senior Software Engineers to design, develop, test, and maintain software for scientific and laboratory applications in a regulated life sciences environment. The role combines full-stack development, architecture, cloud infrastructure, instrument integration, scientific-data visualization, and collaboration with scientists and chemists. The job site is in St. Louis, Missouri, with telecommuting available up to three days per week.

Requirements

Master’s degree in Computer Science, Information Science & Technology, or a closely related technical field.
At least three years of work experience as a software engineer or in a closely related occupation.
At least two years of professional experience in full-stack application development, including server-side systems engineering using Java and user-interface development using React.
At least one year of experience developing software in a regulated life sciences environment under GxP and ISO quality/compliance standards, including data integrity, validation, and documentation.
At least three years of experience building software that integrates with laboratory instruments or devices, including instrument calibration workflows and scientific/chemistry data visualization, in collaboration with scientists.
At least three years of experience deploying application services and configuring scalable infrastructure on Amazon Web Services (AWS).
At least two years of experience delivering software through the full SDLC using Agile/SAFe methodologies, sprint planning, and CI/CD pipelines.
All years of experience may be gained concurrently.

Responsibilities

Design, develop, and test scalable web applications using Java and JavaScript/TypeScript (React) in a regulated life sciences environment.
Architect and model relational and non-relational database schemas for scientific and laboratory data.
Lead high-level system design of microservices and component-based software architectures.
Configure, deploy, and manage secure AWS cloud infrastructure and web services using infrastructure-as-code.
Build software that integrates with laboratory instruments and devices, including instrument calibration workflows and acquisition of scientific measurement data.
Develop data-visualization interfaces that present chemistry and laboratory data to scientists for analysis and decision-making.
Ensure applications meet GxP and ISO quality, validation, and data-integrity standards for regulated certified products.
Collaborate directly with scientists and chemists to translate laboratory, chemistry, and analytical requirements into maintainable software designs.
Apply AI-assisted and agentic developer tooling, such as MCP-based workflows and design-to-code automation, to accelerate delivery.
Conduct code reviews, resolve production issues, prepare technical documentation and architecture diagrams, and mentor peers.