Senior Scientist, Chemical Process Development

Biogen•Cambridge, MA
•$138,000 - $184,500

About The Position

Biogen is seeking a talented and motivated Senior Scientist to join its Chemical Process Development (CPD) group. The role contributes to a multidisciplinary team developing green, safe, and cost-effective batch and continuous chemical processes for producing active pharmaceutical ingredients (APIs) for clinical and commercial purposes. The position calls for hands-on industrial laboratory experience, project management experience—including vendor management—and person-in-plant experience. It also involves supporting technology transfer to external development and manufacturing organizations, with approximately 10% domestic and international travel potentially required.

Requirements

  • Ph.D. in Chemistry and at least 4 years of industry experience; or a research-thesis MS degree in Chemistry and at least 5 years of industry experience; or a bachelor's degree in Chemistry and at least 7 years of industry experience.
  • Hands-on experience in laboratory chemical synthesis and isolation or separation processes.
  • Familiarity with analytical instrumentation for tracking reaction and process performance.
  • Familiarity with mechanistic modeling and online or in-situ Process Analytical Technology.
  • Experience collecting and analyzing data-rich experiments using laboratory reactors equipped with data acquisition and control features.
  • Strong background in chemical synthesis.
  • Experience reviewing technical and cGMP-related documents, including batch records and process development reports.
  • Experience working with contract manufacturing facilities and managing technical transfers.
  • A scientific track record demonstrated through publications and presentations at scientific conferences.
  • Experience as a technical development team member on cross-functional teams advancing assets from research and development into manufacturing.

Nice To Haves

  • Familiarity with plant unit operations and novel manufacturing technologies.
  • Experience with peptide and/or oligonucleotide synthesis and/or purification.

Responsibilities

  • Set up equipment, conduct experiments, analyze data, and write reports and procedures.
  • Participate in team discussions to set experimental objectives and prepare experimental designs and plans.
  • Design and conduct laboratory chemical experiments, then analyze and interpret results to develop scalable processes.
  • Mentor junior scientists and build external collaborations to design experiments and interpret data for scalable process development.
  • Learn, evaluate, and identify technologies relevant to Chemical Process Development activities.
  • Support process technology transfer to external development and manufacturing organizations (CDMOs).
  • Manage key equipment and instrumentation, including regular maintenance and repairs.

Benefits

  • Medical, dental, vision, and life insurance.
  • Fitness and wellness programs, including fitness reimbursement.
  • Short- and long-term disability insurance.
  • At least 15 days of paid vacation and year-end shutdown time off from December 26 through December 31.
  • Up to 12 company-paid holidays and 3 paid days off for Personal Significance.
  • 80 hours of sick time per calendar year.
  • Paid maternity and parental leave.
  • 401(k) program with company-matched contributions.
  • Employee stock purchase plan.
  • Tuition reimbursement of up to $10,000 per calendar year.
  • Employee Resource Groups participation.
  • Short-term and long-term incentives, including cash bonus and equity incentive opportunities, subject to individual, business unit, and company performance.
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