Process Development Senior Scientist

Amgen • Cambridge, MA

7h • $126,066 - $170,560

About The Position

The Process Development Senior Scientist is responsible for inventing, developing, and implementing drug substance manufacturing processes and technologies for Amgen’s synthetic and hybrid assets. Process chemists use their synthetic training to create synthetic routes and chemical processes that support drug substance manufacturing from early- through late-stage development.

The role advances enabling technologies to accelerate pharmaceutical development and improve sustainability and process efficiency. It supports cGMP manufacturing and technology transfer to internal manufacturing facilities and external contract manufacturers, and ensures process performance through process understanding, modeling, and characterization. The scientist contributes experimental results, technical updates, documentation, data interpretation, and recommendations to drug substance development teams; works cross-functionally on regulatory documents and filings; serves as a technical expert in organic and process chemistry; and advances projects and studies independently and within multidisciplinary teams.

Requirements

• Doctorate degree (PhD, PharmD, or MD); or a master's degree and 3 years of industry experience; or a bachelor's degree and 5 years of industry experience.
• Highly motivated.
• Demonstrated ability to work within a dynamic and interdisciplinary environment to achieve results.
• Excellent written and verbal communication skills.
• Ability to multitask, effectively plan, and follow through on complex projects.

Nice To Haves

• Ph.D. in organic chemistry and/or biochemistry, specializing in total synthesis, reaction methodology, mechanistic studies, biocatalysis, peptide chemistry, oligonucleotide chemistry, and/or conjugation chemistry.
• Postdoctoral experience in an academic laboratory or the pharmaceutical/biotech industry.
• Track record of peer-reviewed publications and research presentations.
• A research summary included with the CV is strongly encouraged.

Responsibilities

• Invent synthetic routes and develop safe, robust, and cost-effective processes to manufacture synthetic and hybrid drug substances.
• Advance enabling technologies to accelerate pharmaceutical development and improve sustainability and process efficiency.
• Support cGMP manufacturing and technology transfer to internal manufacturing facilities and external contract manufacturers.
• Ensure process performance through process understanding, modeling, and characterization.
• Contribute experimental results, technical updates, documentation, data interpretation, and recommendations to drug substance development teams.
• Work cross-functionally to deliver regulatory documents and support regulatory filings.
• Serve as a technical expert and keep current in organic and process chemistry.
• Work effectively in a multidisciplinary team of chemists, engineers, and attribute scientists.
• Independently advance projects and studies within required deadlines.

Benefits

• Retirement and Savings Plan with generous company contributions.
• Group medical, dental, and vision coverage.
• Life and disability insurance.
• Flexible spending accounts.
• Discretionary annual bonus program, or a sales-based incentive plan for field sales representatives.
• Stock-based long-term incentives.
• Award-winning time-off plans.
• Flexible work models where possible.
• Career development opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Ph.D. or professional degree