Senior Scientist, Chemical Process Development

Biogen•Cambridge, MA

About The Position

Biogen is seeking a talented, highly motivated Senior Scientist to join its growing Chemical Process Development (CPD) group. This role is part of a multidisciplinary team developing green, safe, and cost-effective batch and continuous chemical processes to produce active pharmaceutical ingredients for clinical and commercial purposes. The ideal candidate has hands-on industrial laboratory experience and project management experience, including vendor management and person-in-plant experience. The Senior Scientist performs laboratory experiments and data analysis, prepares reports and procedures, contributes to experimental objectives and designs, and develops scalable chemical processes. The role also includes mentoring junior scientists, building external collaborations, evaluating technologies relevant to CPD, supporting process technology transfer to external development and manufacturing organizations, and managing equipment and instrumentation, including maintenance and repairs. Domestic and international travel of approximately 10% may be required.

Requirements

Ph.D. in Chemistry and at least 4 years of industry experience; alternatively, a Chemistry M.S. that includes completion of a research thesis and at least 5 years of industry experience; or a Chemistry bachelor's degree and at least 7 years of industry experience.
Hands-on experience in laboratory chemical synthesis and isolation or separation processes.
Familiarity with analytical instrumentation for tracking reaction and process performance.
Familiarity with mechanistic modeling and online or in-situ Process Analytical Technology.
Experience collecting and analyzing data-rich experiments using laboratory reactors equipped with data acquisition and control features.
Strong background in chemical synthesis.
Experience reviewing technical and cGMP-related documents, including batch records and process development reports.
Experience working with contract manufacturing facilities and managing technical transfers.
Proven scientific track record through publications and presentations at scientific conferences.
Experience as a technical development team member on cross-functional teams progressing assets from research and development into manufacturing.
Industrial laboratory and drug development experience.
Project management experience, including vendor management and person-in-plant experience.

Nice To Haves

Familiarity with plant unit operations and novel manufacturing technologies.
Experience with peptide and/or oligonucleotide synthesis and/or purification.
Experience with peptide or oligonucleotide synthesis and/or purification is a plus.

Responsibilities

Set up equipment, conduct experiments, analyze data, and write reports and procedures.
Participate in team discussions to establish experimental objectives and prepare experimental designs and plans.
Design and conduct laboratory chemical experiments, then analyze and interpret results to develop scalable processes.
Mentor junior scientists and build external collaborations to design experiments and interpret data for scalable process development.
Learn about, evaluate, and identify technologies relevant to Chemical Process Development activities.
Support process technology transfer to external development and manufacturing organizations (CDMOs).
Manage key equipment and instrumentation, including regular maintenance and repairs.
Travel domestically and internationally, as required, approximately 10% of the time.

Benefits

Medical, dental, vision, and life insurance.
Fitness and wellness programs, including fitness reimbursement.
Short- and long-term disability insurance.
At least 15 days of paid vacation and additional end-of-year shutdown time off from December 26 through December 31.
Up to 12 company-paid holidays and 3 paid days off for Personal Significance.
80 hours of sick time per calendar year.
Paid maternity and parental leave.
401(k) program with company-matched contributions.
Employee stock purchase plan.
Tuition reimbursement of up to $10,000 per calendar year.
Short-term and long-term incentive opportunities, including cash bonus and equity incentives, for eligible regular employees.
Employee Resource Groups participation.