Senior Scientist - Surface Plasmon Resonance (SPR) and Characterization
IQVIA•Durham, NC
•$80,200 - $167,200•Onsite
About The Position
The Senior Scientist will lead high‑throughput biophysical characterization of antibodies generated from discovery and affinity maturation campaigns, supporting the selection of high‑quality therapeutic leads through advanced biomolecular interaction analyses.
Requirements
- PhD with relevant experience or MS with 3+ years of experience in Biology, Biochemistry, Molecular Biology, Chemical Engineering, Immunology, or a related life science field, preferably within biotech or pharmaceutical environments.
- Extensive hands‑on experience with protein–protein interaction analysis using label‑free biosensor technologies
- Mastery of SPR platforms with demonstrated experience using Carterra LSA and Biacore 8K systems
- Strong understanding of antibody biophysical characterization and developability considerations
- Ability to operate, maintain, and troubleshoot complex SPR instrumentation independently
- Excellent analytical, communication, and leadership skills with the ability to manage multiple priorities
Nice To Haves
- Experience with BLI instrumentation and automated laboratory systems is a plus
- Other Equivalent combination of education, training, and experience may be accepted in lieu of degree
Responsibilities
- Perform full biophysical characterization of antibodies from discovery and affinity maturation campaigns in a high‑throughput environment
- Supervise, train, and mentor team members in the design and execution of biomolecular interaction analyses
- Independently design, execute, and troubleshoot SPR‑ and BLI‑based assays including kinetics, affinity, blocking, competition, and epitope binning
- Analyze, interpret, and present complex data sets to support antibody lead selection across multiple concurrent programs
- Develop, optimize, and standardize novel assays to support custom antibody discovery workflows
- Collaborate with Discovery and Bioinformatics teams to guide R&D efforts related to antibody developability
Benefits
- Integrated benefits programs and resources to take care of our employees’ physical, mental and emotional, financial and social well-being
Stand Out From the Crowd
Upload your resume and get instant feedback on how well it matches this job.
Upload and Match Resume
What This Job Offers
Job Type
Full-time
Career Level
Senior
