Senior Scientist- Surface Biology Early Validation

Amgen • Thousand Oaks, CA

17h

About The Position

Join Amgen’s Mission of Serving Patients At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. Senior Scientist – Surface Biology Early Validation What you will do Let’s do this. Let’s change the world. We are seeking an experienced Senior Scientist to support early validation of membrane protein targets through development and application of quantitative, cell-based assays. In this role, you will contribute to building and executing scalable experimental workflows that generate high-quality data on target expression, localization, and behavior in cellular systems. You will work closely with cross-functional partners to support discovery efforts across Therapeutic Areas.

Requirements

• Doctorate degree OR Master’s degree and 2 years of scientific experience OR Bachelor’s degree and 4 years scientific experience OR Associate’s degree and 8 years scientific experience OR High school diploma / GED and 10 years scientific experience

Nice To Haves

• PhD in Cell Biology, Molecular Biology, or related discipline
• 2+ years of relevant industry experience, including leadership of scientific projects or teams
• Strong expertise in flow cytometry, imaging, and cellular assay development
• Experience working with membrane proteins or receptor biology
• Experience with scalable or high-throughput assays workflows
• Familiarity with molecular biology techniques or genome editing approaches to support assay design
• Strong data analysis, troubleshooting, and problem-solving skills
• Effective collaboration and communication skills

Responsibilities

• Design and execute scalable cell-based assays to assess membrane protein expression, localization, and internalization
• Apply flow cytometry-based approaches to generate quantitative and reproducible data
• Integrate complementary approaches such as imaging-based assays to support target evaluation
• Develop and optimize assays for robustness, scalability and consistency
• Analyze and interpret experimental data to support target evaluation
• Collaborate with cross-functional teams to integrate findings into discovery programs
• Maintain high standards of experimental rigor and documentation

Benefits

• health and welfare plans for staff and eligible dependents, financial plans with opportunities to save towards retirement or other goals, work/life balance, and career development opportunities
• Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree
• Number of Employees: 5,001-10,000 employees