Senior Scientist, Regenerative Medicine

Bio-Techne • Minneapolis, MN

4d

About The Position

By joining Bio-Techne, you’ll join a company with a powerful and positive purpose of enabling cutting-edge research in Life Sciences and Clinical Diagnostics. Bio-Techne, and all of its brands, provides tools for researchers to further treat and prevent disease worldwide. Pay Range: $87,600.00 - $144,000.00 Senior Scientist, Regenerative Medicine – Customer Applications Position Summary: The Regenerative Medicine – Customer Applications Senior Scientist is a key member of a dynamic team focused on developing innovative products and applications for regenerative medicine and organoid research. We are seeking a highly skilled and experienced scientist with demonstrated expertise in diverse organoid workflows, disease modeling, and driving innovation for stem cell-derived therapies. The successful candidate will play a critical role in developing and improving human pluripotent stem cell (hPSC)-based differentiation and characterization techniques. As a part of this role, you’ll help drive significant progress in regenerative and personalized medicines by joining a collaborative team of innovators working to create impactful solutions for drug discovery and clinical trials. This position offers a unique opportunity to utilize the breadth of Bio-Techne’s product portfolio and work closely with various teams to maximize the impact of our reagent solutions. Key responsibilities include developing products and applications for expansion, differentiation, and characterization of stem cell derived organoid models. Experience in culturing stem cells (e.g. iPSC, ESC, MSC or adult stem cells) and in 3D culture systems, including spheroid, organoids - is required.

Requirements

• Ph.D. in Biology, Biomedical Engineering, Chemical Engineering, or a related field, with a minimum of 2+ years of industry experience in cell and gene therapy, regenerative medicine, or biomanufacturing.
• Proven expertise in process development for stem cell-based therapy research, including scaling workflows from discovery to GMP-compliant manufacturing.
• Hands-on experience with adherent cell culture systems and advanced bioreactor platforms for large-scale cell expansion and differentiation.
• Significant technical expertise/scientific knowledge of autologous or allogeneic cell therapies or differentiation pathways.
• Expertise in fluorescence microscopy and standard cell characterization assays (e.g. RT-PCR, flow cytometry, ELISA, and ICC) required.
• Strong background in developing and optimizing differentiation protocols for iPSCs or other pluripotent stem cells, with an emphasis on clinical and manufacturing applications.
• Self-motivated, action oriented, highly collaborative and team focused, results driven with high levels of professionalism, responsibility and positive attitude.
• A strong track record of independence, scientific productivity, and creative problem-solving.
• Knowledge of regulatory and quality standards for GMP production and experience developing workflows under design control and risk-based approaches.
• Technical proficiency with standard cell characterization assays, 3D culture systems, and advanced imaging or high-throughput screening platforms.
• Demonstrated ability to lead cross-functional teams, manage complex projects, and provide innovative solutions to technical challenges.
• Track record of scientific innovation, productivity, and problem-solving in a fast-paced, results-driven environment.

Nice To Haves

• The ideal candidate has translational research experience applying organoid models to disease biology, drug discovery, and/or therapeutic screening.
• Experience with gene editing technologies (e.g. CRISPR) and biomaterials for advanced cell culture a plus.
• Prior demonstrated experience developing and validating/verifying product workflows under design control using a requirements-driven, risk-based approach within the biotech industry or clinical laboratory.
• High throughput assays or high content imaging experience strongly preferred.

Responsibilities

• Identify and develop products, workflows, and key culture optimizations (i.e. expansion, differentiation, and characterization) for stem cell-based therapy and organoid research and application.
• Develop and optimize robust and reproducible cell differentiation protocols, analytical methods, and other processes needed to convert human induced pluripotent stem cells (iPSCs) into cellular products and therapeutics.
• Lead core teams and collaborate with cross-functional teams to formulate cell differentiation reagents and protocols for different iPSC-derived cell types.
• Serve as a subject matter expert in organoids, supporting new product initiatives including organoid model development, disease modeling applications, drug screening platforms, and protocol scale-up.
• Develop cell-based, biochemical, and/or molecular assays to characterize the identity and physiology of stem cell-derived differentiated cells and organoids.
• Plan and perform experiments, analyze data, and generate presentations to inform project progress to wider department and leadership.
• Provide substantial, high-quality contributions to projects by working independently, communicating effectively within cross-functional team and leverage available expertise and support across the organization.
• Contribute to corporate scientific activities/roadmaps/strategy.
• Develop scientific content including conference presentations, publications, application notes, webinars and other Sales and Marketing efforts to support and promote Bio-Techne’s stem cell, organoids, and regenerative medicine product offerings and services.
• Apply scientific methods and process design principles to improve development, manufacturing and quality control processes.
• Author documentation including standard operating procedures (including Manufacturing and QC) for RUO and GMP products, design verification and validation procedures, and technical reports to support lab operation, development initiatives, and product investigations.
• Stay up to date with the latest scientific developments and market offerings in the fields of stem cell, organoids, and regenerative medicine.
• Provide subject matter expertise, mentorship, and leadership to other scientists and research associates across the department and the wider Bio-Techne team.

Benefits

• We offer competitive insurance benefits starting on day one: medical, dental, vision, life, short-term disability, long-term disability, pet, and legal and ID shield.
• We invest in our employees’ financial futures through 401k plans, an employee stock purchase plan (ESPP), Health Saving Account (HSA), Flexible Spending Account (FSA), and Dependent Care FSA.
• We empower our employees develop their careers through mentorship, promotional opportunities, training and development, tuition reimbursement, internship programs, and more.
• We offer employee resource groups, volunteer paid time off, employee events, and charity drives to build a culture of caring and belonging.
• We offer an accrued leave policy with paid holidays, paid time off, and paid parental leave.
• We foster a culture of empowerment and innovation, where employees feel valued and encouraged to bring their new ideas to the table.

What This Job Offers

• Job Type: Full-time
• Career Level: Mid Level
• Education Level: Ph.D. or professional degree