Principal Scientist - Precision Medicine

Regeneron Pharmaceuticals • Tarrytown, GA

4d • Onsite

About The Position

The Precision Medicine group at Regeneron is responsible for designing, implementing, executing, analyzing and interpreting the overarching clinical biomarker strategies for therapeutic candidates during clinical development. We are seeking to hire a Precision Medicine Strategy Lead (PMSL) at the Principal Scientist level to oversee the development and execution of biomarker strategies for multiple clinical stage assets across diverse therapeutic areas including solid tumor oncology, heme malignancies, immune oncology, rare genetic disorders and/or neurodegenerative conditions.

Requirements

• Master's degree with 7 years of experience (Ph.D. DrPH, M.D. with 4+ years of experience) participating effectively on cross-disciplinary teams in pharmaceutical or biotech industry.
• Experience in clinical assay development, validation and implementation, with a track record of high impact in drug development.
• Ability to drive, manage, execute and deliver results for complex multi-functional projects
• Excellent communication and presentation skills and high emotional intelligence, organizational skills and effective team skills
• Strategic understanding of the application of biomarker technologies to basic, translational or clinical research
• Demonstrated ability to ensure timely delivery of results across selected programs

Nice To Haves

• Experience in solid tumor oncology or heme malignancies with exposure to clinical development experience is preferred.
• Familiarity with complex datasets, molecular epidemiology and/or statistics a plus.

Responsibilities

• Program-level PM lead for implementation of strategic vision for clinical biomarkers in one or more therapeutic areas that will broadly enable advances in target identification, indication selection, early indication of biological activity and patient stratification/selection
• Serve as an individual contributor and representative of Precision Medicine on development teams and deliver biomarker strategies to key programs from initial concept to execution, data delivery and results interpretation
• Collaborate with Discovery Research and product development teams to facilitate appropriate incorporation of Precision Medicine and clinical biomarker strategies for molecules in discovery phases (leading to candidate molecule selection)
• Represent Regeneron and work with colleagues from allied companies to develop and implement strategies for partnered alliances
• Collaborate with clinical operations teams to implement specific biomarker and exploratory sample collection and analyses in all relevant clinical studies in selected programs
• Design, oversee and manage internal and external research collaborations in areas of clinical technologies and translational research
• Accountability for ensuring clinical assays used in programs are fit-for-purpose (whether developed and validated internally or externally)
• Collaborate with internal Regeneron laboratories (e.g. Discovery Research, Molecular Profiling, Regeneron Genetics Center, DNA Core, BioAnalysis, etc.) to develop plan for validation and application of research assays
• Contribute to and ensure the quality of Precision Medicine technical reports, study memos and clinical study reports, data reviews and interpretations, scientific publications and recommendations to development teams and management

Benefits

• health and wellness programs (including medical, dental, vision, life, and disability insurance)
• fitness centers
• 401(k) company match
• family support benefits
• equity awards
• annual bonuses
• paid time off
• paid leaves (e.g., military and parental leave)

What This Job Offers

• Job Type: Full-time
• Career Level: Principal