Senior Scientist – RC Discovery Biology

AstraZeneca•Hamilton, ON

39d•$108,714 - $142,687•Onsite

About The Position

As a Senior Scientist in radioconjugate drug discovery, this role drives innovative research at the interface of tumor and radiation biology. Fully competent in a defined Bioscience area, this position initiates, directs and performs complex experiments, shapes scientific strategy, and supports project progression from early discovery towards the clinic. Working with limited supervision, this role also advises and trains less experienced scientists and may take on supervisory responsibilities without formal line management.

Requirements

PhD Degree with 3+ years of experience, Master’s Degree with 5+ years of experience, or a Bachelor’s Degree with 7+ years and project leadership experience in a relevant discipline related to tumor and radiation biology
Proven track record of contributing to multidisciplinary project teams, influencing scientific direction and delivering data that supports progression decisions.
Strong communication skills, with experience presenting complex scientific concepts to diverse audiences and preparing materials for governance or external interactions.
Demonstrated ability to mentor or guide junior scientists in experimental design, data analysis and scientific thinking.

Nice To Haves

Radioconjugate experience, including hands-on work with targeted radioconjugate platforms or radioligand-based assays.
Experience in the biopharmaceutical or biotechnology industry, ideally within oncology or radiopharmaceutical drug discovery.

Responsibilities

Serve as an independent technical lead for radioconjugate programs, collaborating with cross-functional teams and external partners to generate critical program data for project milestone decisions
Executes radioconjugate (RC) drug discovery research experiments independently in the lab by applying the techniques of molecular and cellular biology, radiation biology, mechanism of action studies and immunohistochemistry
Lead preclinical in vitro pharmacology studies, including radioligand binding, internalization, and retention assays; supports in vivo pharmacology through study designs and data interpretation
Analyzes and presents results to core project teams, prepares materials for governance interactions, and deliver program updates across internal forums
May lead radioconjugate portfolio projects and/or support a project team and work collaboratively with project managers to ensure the efficient relay of information and forward translation of data
Assesses and reports data, with little or no guidance, in a clear and concise manner, with a clear understanding of its implications within the overall context of drug discovery projects
Stay up-to-date with technical, intellectual, and scientific expertise in cancer biology and modeling, particularly related to targeted radioconjugates
Coordinates project activities and provides scientific mentorship to junior scientists
Ensures own work, and work of peers, is compliant with Good Laboratory Standards (GLS), Safety, Health and Environment (SHE) standards, Radiation Safety and all other relevant internal AstraZeneca standards and external regulations

Benefits

Recognizing the importance of individualized flexibility, our ways of working allow employees to balance personal and work commitments while ensuring we continue to create a strong culture of collaboration and teamwork by engaging face-to-face in our offices 3 days a week.
Our head office is purposely designed with collaboration in mind, providing space where teams can come together to strategize, brainstorm and connect on key projects.
GTAA Top Employer Award for 11 years
Top 100 Employers Award
Canada’s Most Admired Corporate Culture
Annual base salary for this position ranges from 108,713.60 to 142,686.60.
AstraZeneca is committed to providing fair and equitable compensation opportunities to all colleagues.
Our compensation policies and practices have been designed to allow colleagues to progress through the salary range over time as they progress in their role.
The range provided in this posting represents an offer pay range used in a majority of situations.
The base pay offered will vary depending on multiple individualized factors, including the candidate's skills and experience, job-related knowledge, and other specific business and organizational needs.
In some cases, offers outside the range may also be considered to address unique circumstances.
In addition, our permanent positions offer an annual Variable Pay Bonus/Short Term Incentive opportunity as well as eligibility to participate in our equity-based long-term incentive program (if applicable to role).
Benefits offered for permanent roles include a competitive Flex Benefits & Retirement Savings Program, 4 weeks’ paid vacation, and annual Personal Days.