Senior Scientist, Non-Viral Delivery Attribute Sciences

Bristol Myers Squibb • Cambridge, MA

7d • $142,220 - $172,340 • Onsite

About The Position

Bristol Myers Squibb is seeking a scientifically curious Senior Scientist to help grow its Attribute Sciences capability and establish mechanistic understanding that supports next-generation targeted lipid nanoparticle (LNP) development. The role integrates cell biology, delivery science, and advanced characterization to define product attributes and biological mechanisms governing targeted LNP performance. The scientist will integrate scientific datasets, expand characterization capabilities through emerging technologies, and work across Research and CMC to translate mechanistic insights into product development and program decisions.

The position is within the Non-Viral Delivery Research team in the Cell Therapy Thematic Research Center, whose mission is to develop engineered cell-based therapies and harness the immune system to improve patient outcomes. The successful candidate will bring strong cell biology and functional assay development expertise, scientific curiosity across disciplines, and an interest in applying mechanistic understanding to targeted therapeutics.

Requirements

• Bachelor’s degree and 7 or more years of academic and/or industry experience; or a master’s degree and 5 or more years; or a Ph.D. or equivalent advanced degree in the Life Sciences and 2 or more years.
• Strong background in cell biology or a related biological discipline.
• Demonstrated experience developing and applying cell-based assays to characterize biological activity and functional performance.
• Ability to work effectively in multidisciplinary teams and in a highly collaborative, cross-functional research environment.
• Strong scientific communication skills, including the ability to explain complex data and mechanistic insights clearly to project teams, senior leadership, and other audiences.

Nice To Haves

• Ph.D. in Cell Biology, Molecular Biology, Immunology, Biochemistry, Bioengineering, Pharmaceutical Sciences, or a related discipline with 2 or more years of relevant industry experience; alternatively, an M.S. with 5 or more years or a B.S. with 7 or more years of relevant experience.
• Experience with primary cells, multiparametric flow cytometry, or other advanced cellular characterization approaches.
• Experience with complex drug products, biologics, nanoparticle delivery systems, or related therapeutic modalities.
• Experience applying analytical, biophysical, and cellular characterization approaches to support mechanistic product understanding and establish attribute–performance relationships.
• Experience with high-throughput, automated, or scalable experimental approaches.

Responsibilities

• Advance scientific frameworks and characterization capabilities that support non-viral delivery product and platform development.
• Develop biologically relevant cellular characterization strategies, including primary and patient-derived cell systems, to understand how product attributes and biological context influence functional performance.
• Lead attribute characterization for formulation and process changes, comparability assessments, and technical investigations; partner with Analytical Development, Process Sciences, and Product Development to assess impacts on product quality and functional performance.
• Develop and implement high-throughput and automated characterization approaches to improve experimental throughput, reproducibility, and scalability.
• Partner with Analytical Development to identify and expand internal and external characterization capabilities for targeted LNP drug products, including emerging technologies and methodologies.
• Collaborate across Research and CMC functions and represent Attribute Sciences on program and CMC teams, providing scientific expertise to inform product development and program decisions.
• Communicate scientific findings and actionable recommendations to multidisciplinary teams and leadership to influence delivery strategy and program decisions.
• Mentor junior scientists and contribute to developing new experimental approaches and technologies.

Benefits

• Comprehensive benefit plans, including wellbeing support, retirement and financial protection benefits, and medical, dental, vision, life, and disability insurance offerings.
• Flexible Time Off without a set accrual limit for eligible U.S.-based exempt employees, subject to manager approval.
• Eleven paid company holidays each year.
• For specified non-exempt employees, RayzeBio employees, and employees located in Puerto Rico: 160 hours of paid vacation annually for new hires, subject to manager approval, 11 paid company holidays, and 3 optional holidays.
• Depending on eligibility, paid sick leave, up to two paid volunteer days per year, summer-hours flexibility, and leaves of absence for medical, personal, parental, caregiver, bereavement, or military needs.
• Eligible employees may receive an annual Global Shutdown between Christmas Day and New Year's Day.
• Potential eligibility for discretionary incentive cash and stock opportunities.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior