Senior Scientist I/II - Oncology
About The Position
The xDC Biotherapeutics group within Oncology Drug Discovery at Novartis Biomedical Research is seeking a highly motivated and collaborative Senior Scientist I/II to advance drug-conjugate discovery programs for the treatment of cancer patients. In this lab-based role, the successful candidate will apply cell and molecular biology techniques to deliver impactful data for target validation and drug optimization efforts. This role requires a strong understanding of and experience with in vitro cell-based assays for drug discovery. This individual will interact collaboratively with colleagues across Biomedical Research and will be a member of multidisciplinary project teams. This is a great opportunity to join a group dedicated to the discovery of biotherapeutics and to support advancement of drug discovery projects into the Novartis portfolio.
Requirements
- BS/MS Degree in biology or related field
- Minimum 5+ years of industry experience preferred
- Extensive experience with cellular assay development & execution, experience with high throughput screening workflows strongly preferred
- Demonstrated ability to analyze, interpret and present data in a clear manner and use data to generate new hypotheses
- Highly self-motivated, collaborative team player with exceptional organizational skills and curiosity to expand and diversify skillsets
- Level will commensurate with experience
Nice To Haves
- Understanding of drug discovery optimization processes
- Experience with discovery of antibody-drug-conjugates
Responsibilities
- Generates hypotheses to test, troubleshoots issues and designs and executes the next set of experiments with some input from senior lab members/manager.
- Works independently and as a part of a team to design, execute, and analyze in vitro experiments to profile small molecules and biologics and elucidate mechanisms of action
- Executes cell and molecular biology assays (e.g. cell titer glo, flow cytometry, JESS, western blot, MSD)
- Cultures cells using sterile technique including genetic engineering and validation of cell lines
- Uses laboratory automation equipment (liquid handlers, plate readers, dispensers) to perform screens
- Maintains an organized and detailed record of all experiments
- Works collaboratively across teams and trains other members of team in areas of technical expertise as needed.
- Clearly communicates findings and presents research to multidisciplinary project teams
- Supports lab operations including management of materials, maintenance of instruments, and general lab duties
Benefits
- health, life and disability benefits
- a 401(k) with company contribution and match
- a variety of other benefits
- a generous time off package including vacation, personal days, holidays and other leaves
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What This Job Offers
Job Type
Full-time
Career Level
Mid Level
Education Level
Associate degree
