Principal Scientist I, Oncology Pharmacology

Novartis

2d • $93,800 - $174,200 • Onsite

About The Position

Imagine being at the forefront of breakthrough oncology research, where your work directly shapes the next generation of cancer therapies. In this role, you will play a key part in advancing innovative drug candidates by developing and applying cutting-edge in vivo pharmacology approaches. Working within a dynamic and highly collaborative research environment, you will contribute to the design and execution of preclinical studies, generating critical data that drives decision-making and accelerates the journey of new treatments toward patients. This is an opportunity to combine scientific expertise with real-world impact—helping reimagine medicine for people living with cancer.

Requirements

• Bachelor’s or master’s degree in pharmacology, biology, biochemistry, or a related life science discipline
• Strong hands-on experience with rodent handling and in vivo pharmacology techniques, including multiple dosing routes
• Proven experience with preclinical oncology models and development of in vivo tumor models
• Proficiency in cell culture techniques, including cell maintenance, passaging, and harvesting
• Ability to design, execute, and interpret pharmacology studies with strong attention to detail and data accuracy
• Effective collaboration, communication, and multitasking skills within a fast-paced, matrixed research environment

Nice To Haves

• Hands-on experience with advanced ex vivo pharmacodynamic assays, including flow cytometry, enzyme-linked immunosorbent assay, or polymerase chain reaction
• Experience using data analysis and visualization tools such as GraphPad Prism for pharmacology data interpretation

Responsibilities

• Design, execute, and analyze in vivo and ex vivo pharmacology studies for oncology drug development
• Develop and utilize preclinical tumor models to evaluate efficacy and safety of novel therapies
• Perform animal handling procedures, including dosing, tumor measurement, and tissue and blood collection
• Apply cellular and biochemical assays to interpret pharmacodynamic responses and support study outcomes
• Ensure accurate data recording, documentation, and adherence to good laboratory practices
• Present scientific findings clearly in team, department, and cross-functional project meetings
• Collaborate effectively within a matrixed research environment to advance oncology programs

Benefits

• health, life and disability benefits
• a 401(k) with company contribution and match
• a variety of other benefits
• a generous time off package including vacation, personal days, holidays and other leaves
• performance-based cash incentive
• eligibility to be considered for annual equity awards

What This Job Offers

• Job Type: Full-time
• Career Level: Principal
• Education Level: Associate degree