Senior Research Associate = High Throughput Cellular Pharmacology

Monte Rosa Therapeutics, IncBoston, MA
$90,000 - $115,000

About The Position

Monte Rosa Therapeutics is seeking a motivated High Throughput Cellular Assay expert to contribute to our mission of eliminating disease-causing proteins through targeted protein degradation, an innovative approach that enables us to target proteins once considered undruggable. The ideal candidate will have strong expertise in developing high-throughput cellular assays for screening and compound profiling. You will join a fast-paced and innovative team environment that values teamwork, collaboration, and scientific rigor.

Requirements

  • MS or Ph.D. with in Molecular Biology, Biochemistry, Biology, or related field.
  • The Senior Research Associate II level will have 4-6 years of relevent industrial experience and a Scientist wiill pocess 1-2 years industrial exerience
  • A thorough understanding of assay principles is required
  • Hands-on experience developing and executing cellular assays for lead discovery and optimization is required. Relevant assay formats include NanoBRET, cellular HTRF, AlphaLISA, HiBiT, and NanoBiT, Degradation Kinetics.
  • Strong collaborative mindset with the ability to thrive in a team-oriented setting.
  • Ability to adapt effectively to rapidly approaching deadlines in a dynamic research environment.
  • Excellent oral and written communication skills.

Nice To Haves

  • Experience working in a drug discovery environment is preferred.
  • Experience with compound screening formats, laboratory instrumentation and automation, data analysis and management is preferred.

Responsibilities

  • Culture a variety of cell lines and primary cells to develop and optimize high-throughput cellular assays to evaluate target engagement, degradation and pathway modulation
  • Utilize automation system to execute cell-based screening and profiling campaigns
  • Collaborate within a matrixed environment that integrates multiple functions to drive program decisions.
  • Keep meticulous records of experiments on ELN.
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