Senior Research Associate, Foundry (Contract)

Tessera TherapeuticsSomerville, MA

About The Position

This role contributes to the optimization and continuous improvement of DNA production workflows and processes. The Senior Research Associate will perform DNA assembly, analyze and interpret experimental data, and ensure accurate reporting and documentation. This position will collaborate with the automation team to develop, optimize, and implement laboratory protocols, and work cross-functionally with R&D, analytical, and bioinformatics teams to support project objectives and timelines. The role also involves participating in team meetings, contributing to the planning and execution of new initiatives and projects, and staying current with advancements in DNA technologies and molecular biology research. Additionally, the position supports day-to-day laboratory operations by maintaining equipment, managing inventory, and coordinating the ordering and receiving of laboratory supplies.

Requirements

  • BS in Biology, Chemistry, Biochemistry, Biotechnology or related field with 2+ years of industry experience; or MS in these fields with 0-2 years of industry experience
  • Strong foundation in molecular biology techniques and cloning workflows
  • Expertise in different cloning methodologies such as Gibson, Golden-Gate, and Site-Directed Mutagenesis (SDM)
  • Execution of end-to-end plasmid workflows including design, assembly, transformation, screening, and sequence verification
  • Performing plasmid QC (DNA quantification, Sanger sequencing, and residual protein) and maintaining inventory for downstream applications
  • Proficiency with software tools such as Benchling, Geneious, or similar
  • Accurate record keeping of experimental data and maintenance of detailed electronic notebooks
  • Adhere to laboratory safety guidelines, SOPs, and regulatory requirements
  • Excellent organizational skills, attention to detail, and ability to manage multiple priorities in a fast-paced environment
  • Ability to work independently as well as part of a collaborative team

Nice To Haves

  • Experience with automated liquid handlers and high-throughput workflows is preferred

Responsibilities

  • Contribute to the optimization and continuous improvement of DNA production workflows and processes
  • Perform DNA assembly, analyze and interpret experimental data, and ensure accurate reporting and documentation
  • Collaborate with the automation team to develop, optimize, and implement laboratory protocols
  • Work cross-functionally with R&D, analytical, and bioinformatics teams to support project objectives and timelines
  • Participate in team meetings and contribute to the planning and execution of new initiatives and projects
  • Stay current with advancements in DNA technologies and molecular biology research
  • Support day-to-day laboratory operations by maintaining equipment, managing inventory, and coordinating the ordering and receiving of laboratory supplies

Benefits

  • Tessera provides reasonable accommodations to qualified applicants and employees with disabilities.
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