Contract – Senior Research Associate

Cytokinetics • South San Francisco, CA

2d • $54 - $63 • Onsite

About The Position

Cytokinetics is a specialty cardiovascular biopharmaceutical company, building on its over 25 years of pioneering scientific innovations in muscle biology, and advancing a pipeline of potential new medicines for patients suffering from diseases of cardiac muscle dysfunction. We are seeking a highly motivated Research Associate with a focus on Drug Metabolism and Pharmacokinetics (DMPK) to join our team. The ideal candidate will contribute to our efforts in pharmacokinetics screening, plasma protein binding, and microsomal assays. This role offers an exciting opportunity to work in a collaborative and fast-paced environment, supporting the development of cutting-edge therapies for cardiovascular and skeletal muscle disorders.

Requirements

• Bachelor's with 3 to 5 years of experience or Master's degree in Pharmaceutical Sciences, Chemistry, Biochemistry, or a related field with 2 to 4 years.
• Proven analytical and problem-solving skills, with the ability to critically evaluate and interpret experimental data.

Nice To Haves

• Hands-on experience with DMPK assays, including screening, plasma protein binding, and microsomal assays are preferred but not required.

Responsibilities

• Bioanalysis: plasma and tissue processing/analysis to determine the drug concentration using the Sciex LC/MS-MS.
• Plasma Protein Binding Studies: Conduct experiments to determine the binding affinity of compounds to plasma proteins using Sciex LC/MS-MS
• Microsomal Assays: Perform microsomal stability studies to assess the metabolic stability and run the assay using the Sciex LC/MS-MS
• Data Analysis and Interpretation: Analyze experimental data using appropriate software (WNL) and statistical methods and provide clear and concise summaries of findings to support decision-making.
• Documentation and Reporting: Maintain detailed records of experimental procedures, results, and observations in laboratory notebooks and electronic databases. Prepare technical reports and presentations for internal meetings and regulatory submissions.
• Collaboration: Collaborate effectively with cross-functional teams, including medicinal chemistry, pharmacology, and toxicology, to support drug discovery and development projects.
• Lab Maintenance: Ensure proper maintenance and organization of laboratory equipment, reagents, and supplies. Adhere to safety protocols and maintain a clean and safe working environment.

Benefits

• Our employees come from different backgrounds, and we celebrate those differences. We are looking for the best candidates for our open roles, but do not expect applicants to meet every qualification in order to be considered. If you are excited about what you could accomplish at Cytokinetics and believe you can add value to our team, we would love to hear from you.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior