Senior Research Associate, Cell Science

Systimmune • Bothell, WA

1d • $70,000 - $90,000 • Onsite

About The Position

SystImmune is seeking a Senior Research Associate in Cell Science to support cell line development through hands-on cell biology, CHO cell line development, and functional assay execution. This is a lab-based role requiring deep experience with CHO cell culture and mammalian expression systems. The associate will work cross-functionally with Protein Engineering and Process Development teams to generate and characterize stable cell lines, support expression of antibody and multi-specific formats, and deliver high-quality data for pipeline programs. The role requires full-time onsite presence at the company’s Bothell, Washington facility.

Requirements

• BS or MS in Cell Biology, Molecular Biology, Biochemistry, or a related field.
• For the Senior Research Associate level: a bachelor’s degree with 5+ years of industry experience or a master’s degree with 3+ years of industry experience.
• Strong background in mammalian cell biology and expression systems.
• Demonstrated hands-on expertise in CHO cell culture and stable cell line development.
• Ability to thrive in a fast-paced team environment and deliver complex objectives under tight deadlines.
• Availability to work weekend and holiday shifts as needed.
• Experience with CHO suspension culture and clone screening.
• Experience with stable transfection methods.
• Cell Biology and Molecular Biology laboratory skills.
• Strong experimental design and troubleshooting skills.

Nice To Haves

• Familiarity with antibody or multi-specific biologics.

Responsibilities

• Maintain mammalian cell cultures.
• Generate and maintain stable CHO cell lines for antibody expression.
• Perform transfection, clone selection, single-cell cloning, and productivity screening.
• Support cell banking activities and maintain detailed documentation.
• Perform expression vector construction, plasmid preparation, and NGS sequencing.
• Analyze and interpret experimental data.
• Maintain accurate electronic lab notebook records.
• Present findings clearly to cross-functional teams.
• Contribute to troubleshooting, assay development, and process improvements.
• Operate effectively in a fast-paced, early-stage R&D environment.

Benefits

• 100% paid employee premiums for medical, dental, and vision insurance.
• Short-term disability insurance.
• Long-term disability insurance.
• 401(k) plan with a 50% company match of up to 3%, with a five-year vesting schedule.
• 15 PTO days per year.
• Sick leave.
• 11 paid holidays.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior