Senior Project Manager

Systimmune•Redmond, WA

1d•$60,000 - $85,000•Onsite

About The Position

SystImmune is seeking a Senior Project Manager, R&D to support cross-functional planning and execution for oncology biologics programs from early discovery through IND-enabling activities and support of IND submission. This role will partner closely with Research, Translational Sciences, Nonclinical, Regulatory, Clinical Pharmacology, and external partners to drive integrated development strategy, stage-appropriate planning, risk management, and operational execution. The ideal candidate brings strong biotech or biopharma drug development experience, excellent cross-functional leadership skills, and a deep understanding of the milestones, dependencies, and decision points required to advance innovative biologics programs into the clinic. This individual will serve as a strategic and operational hub for assigned programs, ensuring alignment, accountability, and timely progress across the portfolio. A key aspect of this role is the effective use of meeting management to strengthen stakeholder integration, communication, decision-making, and execution across internal and external teams.

Requirements

Bachelor’s degree in life sciences, biomedical sciences, chemistry, engineering, or related field
8+ years of relevant experience in biotech, biopharma, or related life sciences industry
5+ years of project or program management experience supporting drug discovery and/or development programs
Demonstrated experience managing biologics programs in oncology or closely related therapeutic areas
Strong understanding of drug development from discovery through IND, including: discovery research and candidate selection, IND-enabling toxicology and pharmacology, CMC and analytical development for biologics, regulatory documentation and IND submission processes
Proven ability to lead highly matrixed, cross-functional teams without direct authority
Excellent communication, facilitation, organizational, and stakeholder management skills
Strong problem-solving abilities with demonstrated experience managing complex timelines, dependencies, and risks
Experience preparing executive-level presentations, status reports, and governance materials

Nice To Haves

Advanced degree (MS, PhD, PharmD, or MBA) in a relevant scientific or business discipline
Experience with monoclonal antibodies, bispecifics, ADCs, or other complex biologic modalities in oncology
Mandarin-English Bilingual Ability
PMP or related project management certification is a plus and biotherapeutics life cycles
Experience in a fast-paced, innovation-driven biotech environment

Responsibilities

Lead cross-functional project planning and execution for oncology biologics programs spanning target/lead discovery, candidate selection, IND-enabling studies, CMC development, and IND submission
Build, maintain, and drive integrated project plans, timelines, milestones, scenarios, and critical path analyses across multiple functional areas
Partner with program leaders and functional heads to define development strategy, key objectives, deliverables, governance milestones, and resource assumptions
Facilitate cross-functional team meetings, sub-team meetings, and governance reviews; document decisions, action items, risks, and next steps
Identify interdependencies, operational risks, and potential bottlenecks early; drive mitigation plans and escalate issues appropriately
Ensure alignment across Research, Nonclinical, CMC, Regulatory, Clinical, Biomarker/Translational, Quality, and partner organizations
Drive program team preparedness for major stage gates, including candidate nomination, development candidate selection, IND-enabling study initiation, and IND submission
Support budget planning, resource tracking, and external partner/CRO coordination as needed
Develop concise and decision-oriented communications for senior leadership, governance bodies, and key stakeholders
Track progress against program goals and proactively highlight deviations, tradeoffs, and decision needs
Promote disciplined program management practices, clear accountability, and efficient team operations
Contribute to portfolio planning and cross-program prioritization discussions where appropriate
Help apply and improve R&D project management tools, templates, dashboards, and best practices
Drive scalable adoption of AI-enabled and digital program management practices, including automation, dashboards, AI-assisted synthesis, standardized workflows, and data-driven reporting, to improve planning, meeting effectiveness, action tracking, knowledge management, risk identification, portfolio governance, and cross-functional execution while ensuring human oversight, data integrity, and compliance.