Senior Project Manager, Operational Readiness

Amgen • Holly Springs, NC

3d • $137,340 - $185,814

About The Position

Join Amgen’s Mission of Serving Patients. At Amgen, if you feel like you’re part of something bigger, it’s because you are. Our shared mission—to serve patients living with serious illnesses—drives all that we do. Since 1980, we’ve helped pioneer the world of biotech in our fight against the world’s toughest diseases. With our focus on four therapeutic areas –Oncology, Inflammation, General Medicine, and Rare Disease– we reach millions of patients each year. Amgen is advancing a broad and deep pipeline of medicines to treat cancer, heart disease, inflammatory conditions, rare diseases, and obesity and obesity-related conditions. As a member of the Amgen team, you’ll help make a lasting impact on the lives of patients as we research, manufacture, and deliver innovative medicines to help people live longer, fuller happier lives. Our award-winning culture is collaborative, innovative, and science based. If you have a passion for challenges and the opportunities that lay within them, you’ll thrive as part of the Amgen team. Join us and transform the lives of patients while transforming your career. SENIOR PROJECT MANAGER, OPERATIONAL READINESS What you will do Let’s do this. Let’s change the world. In this vital role you will have a central role as part of our start up team, leading the planning, execution and tracking of cross-functional activities for our operational readiness workstream, as well as overseeing and ensuring integration and alignment with Construction and Commissioning/Qualification workstreams. Specific responsibilities include developing and integrating readiness plans for multiple workstreams, facilitating activities execution, owning program level forums and governances, resolving execution challenges, ensuring safety, quality and compliance objectives are met. Also, you will be responsible for resource planning and budgeting, active schedule and risk management, project communications, partner alignment, performance tracking, and lessons learned documentation.

Requirements

• High school diploma / GED and 12 years of Project Management experience OR Associate’s degree and 10 years of Project Management experience OR Bachelor’s degree and 6 years of Project Management experience OR Master’s degree and 4 years of Project Management experience OR Doctorate degree and 2 years of Project Management experience.

Nice To Haves

• Experience managing projects in the biopharmaceutical industry, preferably within biotechnology drug substance manufacturing
• Proven ability to translate strategic objectives into clear, executable plans
• Demonstrated leadership skills with the ability to set direction, establish high expectations, and drive performance
• Experience defining workstream scope, roles, and responsibilities, and resolving ownership gaps or conflicts
• Strong ability to build effective working relationships and partnerships across all organizational levels
• Strong communication skills with the ability to engage project teams, workstream leads, senior leadership, and external partners
• Self-starter with the ability to manage multiple projects simultaneously, from daily execution to program-level oversight
• Experience leading large-scale projects within a matrixed organization
• Ability to operate effectively in fast-paced environments with tight timelines
• Strong negotiation and influencing skills across cross-functional stakeholders
• Data-driven decision-maker with strong analytical and problem-solving capabilities
• PMP certification preferred

Responsibilities

• Define project scope and develop operational readiness plans, schedules, and risk registers across key workstreams (Manufacturing, Engineering, Process Development, Supply Chain, Quality Assurance, Quality Control)
• Plan and manage project resources, including forecasting, negotiation, reconciliation, and reporting
• Integrate workstream plans into a consolidated master schedule to define and manage the overall critical path
• Ensure alignment of operational readiness schedules internally and with construction and commissioning/qualification (C&Q) workstreams
• Lead and facilitate execution across workstreams, maintaining accurate and up-to-date schedules
• Proactively identify, manage, and resolve risks and issues; escalate as needed to maintain project milestones and deliverables
• Establish and implement governance structures and tools to ensure effective oversight and decision-making across all workstreams
• Lead cross-functional workshops to drive alignment, resolve challenges, identify gaps, and advance site strategy
• Own the project communication strategy, including standardized tools for tracking, monitoring, and reporting progress
• Provide regular, clear updates to stakeholders, including workstream leads and senior leadership
• Provide strategic guidance to optimize project delivery, proactively de-risk execution, and align with site objectives

Benefits

• A comprehensive employee benefits package, including a Retirement and Savings Plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts
• A discretionary annual bonus program, or for field sales representatives, a sales-based incentive plan
• Stock-based long-term incentives
• Award-winning time-off plans
• Flexible work models where possible.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior