Senior Medical Director, Oncology Clinical Development - GU
About The Position
The Senior Medical Director, Oncology Clinical Development - GU is responsible for clinical research activities that advance GSK’s clinical portfolio and for leading clinical data generation through medical dialogue with internal scientific and medical leaders. The role also leads effective relationships with Key External Experts and requires experience developing and executing oncology clinical trials to support clinical development, regulatory filing, and initial market launch of innovative oncology medicines. The position reports to the Executive Medical Director, Clinical Development Lead, Oncology Clinical Development. The role requires on-site office presence at least two days per week at a GSK site in Zug, Warsaw, Stevenage or London, Cambridge, MA, or another listed US site. For candidates based at Stevenage, the role will temporarily be based there, with a planned relocation to Cambridge, UK, proposed to take effect by early 2029.
Requirements
- Medical degree and completion of advanced specialty training, fellowship, or country-equivalent higher-level qualification in Medical Oncology, Radiation Oncology, Urology, or Internal Medicine with GU or oncology experience.
- Experience in the global pharmaceutical or biotechnology industry in GU prostate cancer.
- Experience leading GU oncology drug development, including Phase 1, 2, and 3 clinical-trial design, initiation, execution, and closure.
- Academic and/or clinical research publication history, or a history of medical practice in GU Oncology.
Nice To Haves
- PhD in addition to a medical degree and advanced specialty training, fellowship, or equivalent higher-level qualification.
- Established professional relationships with Key External Experts in medical oncology and credibility within the medical community.
- Experience clinically assessing business development opportunities to expand a growing portfolio.
- Thorough knowledge of worldwide regulatory and safety requirements for drug development, research projects, and/or market support.
- Strong knowledge of disease-specific research priorities, public health needs, competitor landscape, clinical practice trends, and evolving treatment guidelines.
- Highly developed communication and interpersonal skills for varied audiences and senior stakeholders, supporting effective decision-making in a highly matrixed environment.
- Demonstrated track record of sound decision-making and innovative problem resolution in critical situations.
- Knowledge of regulatory requirements for registration, including knowledge of and adherence to GCP principles.
Responsibilities
- Provide program and cross-functional leadership, collaborating with physicians, scientists, regulatory professionals, biostatisticians, executives, and other colleagues to develop and execute Phase 1–3 interventional clinical trials.
- Represent Clinical Development on disease-area strategy, integrated evidence, and medical affairs strategy teams.
- Oversee high-quality protocols aligned with the Clinical Development Plan to assess efficacy, safety, product differentiation, and patient value efficiently.
- Contribute across the clinical study lifecycle, from protocol concept through final study report, ensuring scientific integrity, timely delivery, alignment with clinical development strategy, global considerations, regulatory approvals, reimbursable medicines, and lifecycle management.
- Interpret and summarize study results, including safety, efficacy, pharmacokinetic/pharmacodynamic, and patient-reported outcomes, and assess applicability to the target patient population.
- Assume medical responsibility for clinical trials, including real-time medical monitoring, patient eligibility assessment, study-design questions, and medical data review.
- Review and monitor safety data in collaboration with the pharmacovigilance group.
- Participate in authoring clinical study reports and regulatory documents, and collaborate with Regulatory Affairs, CMC, Toxicology, Research, and Pharmacology colleagues on health authority and ethics committee queries.
- Collaborate with Principal Investigators to evaluate and assess publications associated with clinical data, including abstracts, posters, and manuscripts.
- Develop long-term strategic partnerships with internal and external thought leaders.
- Contribute to clinical and technical diligence assessments of business development opportunities as needed.
- Understand biological mechanisms, clinical strategy, and scientific interpretation of disease- and target-based literature.
- Represent GSK at medical meetings, advisory boards, and outreach meetings as appropriate.
- Serve as a core member of the Clinical Matrix Team for one or more assets in development.
- Lead Oncology Clinical Development-wide initiatives and workstreams as appropriate.
Benefits
- Annual bonus.
- Eligibility to participate in a share-based long-term incentive program, depending on role level.
- Health care and other insurance benefits for employees and family.
- Retirement benefits.
- Paid holidays and vacation.
- Paid caregiver, parental, and medical leave.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
