Senior Manufacturing Associate - Second Shift

Immatics • Houston, TX

1d • Onsite

About The Position

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics.

Role Overview: We are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities.

Requirements

• Associate’s or Bachelor’s degree in a scientific field (e.g., biology, biotechnology, or related discipline)
• 4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics
• Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D)
• Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standards
• Experience identifying deviations and supporting investigations, CAPAs, and quality systems
• Legal eligibility to work in the United States

Nice To Haves

• Bachelor’s degree in a scientific field
• Experience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniques
• Familiarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)
• Experience supporting validation activities (IQ/OQ/PQ) and change control processes
• Advanced troubleshooting skills and ability to resolve complex manufacturing or equipment issues
• Experience mentoring or training junior staff and contributing to team development
• Demonstrated ability to drive process improvements in a GMP-regulated environment

Responsibilities

• Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing
• Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
• Maintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirements
• Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
• Identify, document, and support investigation of deviations, including CAPA implementation
• Perform calculations, equipment maintenance, and routine manufacturing support activities
• Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives

Benefits

• Competitive rates for Health, Dental, and Vision Insurance
• 4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
• 12 company paid holidays
• 7 days of sick time
• 100% employer-paid life insurance up to 1x annual salary, up to one hundred thousand dollars
• 100% employer-paid short- and Long-Term disability coverage
• 401(k) with immediate eligibility and company match
• Partially paid parental leave for eligible employees.
• Additional voluntary employee-paid benefits and services, including accident, hospital indemnity, and critical illness insurance, as well as identity theft protection and pet insurance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior
• Education Level: Associate degree