Senior Manufacturing Associate - Second Shift

Immatics•Houston, TX

2d•Onsite

About The Position

Join Immatics and shape the future of cancer immunotherapy; one patient at a time! Immatics is committed to making a meaningful impact on the lives of patients with cancer. We are the global leader in precision targeting of PRAME, a target expressed in more than 50 cancers. Our cutting-edge science and robust clinical pipeline form the broadest PRAME franchise with the most PRAME indications and modalities, spanning TCR T-cell therapies and TCR bispecifics. Role Overview We are seeking a Senior Manufacturing Associate to support our CMC-GMP Manufacturing team. In this role, you will lead and execute complex, time-sensitive cell processing and testing activities for patient-derived cellular products in a clinical manufacturing environment. You will be responsible for ensuring compliance with GMP standards, maintaining product integrity and sterility, and overseeing accurate documentation and batch execution. As a senior team member, you will also provide technical guidance, support process improvements, and contribute to maintaining high operational standards across manufacturing activities. Schedule: 1430 – 2300; Monday to Friday Reports to: Manufacturing Manager Location: 13203 Murphy Road Suite 100 Stafford, TX 77477

Requirements

Associate’s or Bachelor’s degree in a scientific field (e.g., biology, biotechnology, or related discipline)
4+ years of experience in GMP-regulated manufacturing, preferably in cell therapy or biologics
Demonstrated experience executing aseptic processing and working in cleanroom environments (Grade A–D)
Proven ability to maintain compliant documentation in accordance with ALCOA++ and cGDocP standards
Experience identifying deviations and supporting investigations, CAPAs, and quality systems
Legal eligibility to work in the United States is required.

Nice To Haves

Bachelor’s degree in a scientific field
Experience in cell therapy manufacturing, including cell culture, cryopreservation, and cell processing techniques
Familiarity with GLP, GTP, and industry standards (e.g., FACT, CAP, CLIA)
Experience supporting validation activities (IQ/OQ/PQ) and change control processes
Advanced troubleshooting skills and ability to resolve complex manufacturing or equipment issues
Experience mentoring or training junior staff and contributing to team development
Demonstrated ability to drive process improvements in a GMP-regulated environment

Responsibilities

Execute and verify cell processing activities, including cell culture, enrichment, cryopreservation, thawing, and washing
Perform manufacturing operations in compliance with GMP, GLP, GTP, and applicable regulatory standards
Maintain accurate, compliant documentation and batch records in line with ALCOA++ and cGDocP requirements
Ensure aseptic handling and cleanroom compliance to maintain product sterility and integrity
Identify, document, and support investigation of deviations, including CAPA implementation
Perform calculations, equipment maintenance, and routine manufacturing support activities
Lead manufacturing runs, mentor junior team members, and contribute to continuous improvement initiatives

Benefits

Competitive rates for Health, Dental, and Vision Insurance
4 weeks of vacation, granted up front each year and prorated for first and last year of employment.
12 company paid holidays
7 days of sick time
100% employer-paid life insurance up to 1x annual salary, up to one hundred thousand dollars
100% employer-paid short- and long-Term disability coverage
401(k) with immediate eligibility and company match
Partially paid parental leave for eligible employees.
Accident insurance
Hospital indemnity insurance
Critical illness insurance
Identity theft protection
Pet insurance