Sr. Manager, Operational Excellence

ModernaTX•Norwood, MA
•$130,800 - $209,400•Hybrid

About The Position

The Senior Manager, Operational Excellence will lead complex, cross-functional improvement efforts across CMC, helping teams solve important business problems, simplify work, and deliver measurable value. As part of a central Operational Excellence team, this role partners with teams and leaders across organizational boundaries to understand complex systems, identify root causes and opportunities, and translate insights into near-term improvements and scalable longer-term solutions. The role combines structured problem solving with digital tools, automation, AI, and emerging technologies, using experimentation and practical approaches focused on business impact. The position operates under Moderna’s 70/30 work model, with 70% in-office collaboration. The work environment is smoke-free, alcohol-free, and drug-free. The salary range is $130,800–$209,400, and the successful candidate may be eligible for a discretionary annual bonus, other incentive compensation, or equity award, subject to plan criteria and individual performance.

Requirements

  • Relevant bachelor's degree in business, operations, engineering, science, or an approved equivalent.
  • At least 6 years of relevant experience driving process improvement, process capability, performance management, and change adoption.
  • Demonstrated knowledge of continuous improvement, structured problem solving, performance management, and change adoption.
  • Ability to navigate ambiguity, exercise sound judgment, and help ensure improvements are adopted, sustained, and deliver expected value.
  • Demonstrated learning agility and ability to quickly grasp new concepts, processes, and technologies.
  • Ability to communicate clearly, manage priorities, and collaborate effectively across disciplines.
  • Full professional proficiency in written and spoken English.

Nice To Haves

  • Experience with Lean, Six Sigma problem solving, Kata coaching, Agile ways of working, or other structured approaches to problem solving and delivery.
  • Lean Six Sigma Green Belt, Black Belt, or equivalent practical experience.
  • Experience applying digital tools, analytics, automation, low-code/no-code solutions, generative AI, or emerging technologies to improve business processes.
  • Experience coaching others in problem solving, continuous improvement, or change adoption.

Responsibilities

  • Lead complex, cross-functional improvement initiatives that address important business problems and deliver measurable outcomes.
  • Structure ambiguous problems by defining the problem, testing hypotheses, identifying root causes, and translating insights into action.
  • Set the improvement approach for multiple complex portfolios, selecting methods based on the problem.
  • Facilitate cross-functional teams and working sessions to build alignment, surface tradeoffs, make decisions, and move from analysis to action.
  • Design practical future states and integrate standard work, measures, ownership, and change adoption across connected processes.
  • Coach teams in rigorous problem framing, root-cause analysis, method selection, and benefit assumptions.
  • Resolve cross-process or portfolio constraints and intervene when local optimization would weaken the broader system.
  • Drive benefit realization and intervene when results are not sustained.
  • Clarify process ownership, decision rights, approvals, and escalation across connected processes.
  • Share and scale effective improvement approaches across teams without adding unnecessary complexity.
  • Continuously explore, experiment with, and adopt digital tools and emerging technologies, including AI, to improve work and deliver value.
  • Perform other reasonable duties related to the role and consistent with skills, training, and experience.

Benefits

  • Competitive healthcare and voluntary benefit programs.
  • Fitness, mindfulness, and mental health support.
  • Family planning benefits, including fertility, adoption, and surrogacy support.
  • Paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
  • Savings and investment programs.
  • Location-specific perks and extras.
  • Potential eligibility for an annual discretionary bonus, other incentive compensation, or equity award.
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