Senior Manager, Health Economics and Outcomes Research – Epidemiology - Cardiovascular, Metabolic, and Rare Diseases
About The Position
Regeneron is seeking a Senior Manager, Epidemiology for its Health Economics and Outcomes Research (HEOR) team, supporting Cardiovascular, Metabolic, and Rare disease programs. The role generates real-world evidence (RWE) to inform development and commercial strategies and collaborates with HEOR colleagues and other key collaborators. It offers the opportunity to contribute to a science-driven organization developing medicines for serious diseases. The position is based in Sleepy Hollow, New York, and requires on-site work four days per week. The role supports regulatory and payer submissions, value dossiers, reimbursement packages, clinical development, evidence generation, and the use of external control arms and hybrid approaches. The Senior Manager also evaluates emerging research methods, advises teams on evolving RWE expectations, and advances projects by identifying solutions and managing priorities.
Requirements
- Doctoral degree in epidemiology or a related subject area, such as health services research or public health.
- At least 2 years of experience across academia, pharmaceutical or biotechnology companies, or consulting.
- Hands-on experience drafting technical design documents, study protocols, and/or statistical analysis plans using real-world data such as claims, electronic health records, or registries.
- Record of peer-reviewed publications.
- Excellent communication skills, including the ability to translate complex research designs and findings into clear, actionable insights for diverse audiences.
Nice To Haves
- Experience conducting epidemiology and real-world evidence research in oncology.
- Familiarity with cardiovascular, metabolic, or rare diseases.
- Experience applying advanced analytical methods to large healthcare datasets, including causal inference, bias assessment, and robust estimation.
- Familiarity with global health technology assessment and payer evidence needs, value strategies, and reimbursement strategies.
Responsibilities
- Generate high-quality observational research using diverse real-world data sources to support development and commercial strategies.
- Evaluate and implement emerging research design and analytic methods to strengthen real-world evidence capabilities.
- Synthesize and critically assess scientific evidence for regulatory and payer submissions, press releases, and internal business needs.
- Provide epidemiology and real-world evidence inputs for global health technology assessment and payer submissions, value dossiers, and reimbursement packages.
- Provide technical expertise to clinical development and evidence generation, including external control arms and hybrid approaches.
- Monitor evolving regulatory and payer expectations for real-world evidence and guide internal teams on their implications.
- Participate in epidemiologic design discussions in a peer review forum.
- Drive projects forward, proactively identify solutions, and manage priorities.
Benefits
- Competitive and comprehensive total rewards package, which may include annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, medical, dental, vision, life and disability insurance, paid time off, and family support benefits, depending on country and role.
- Reasonable accommodation during recruitment for applicants with known disabilities or chronic illnesses where required, unless it would impose undue hardship.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
Education Level
Ph.D. or professional degree
