Executive Director, Health Economics & Outcomes Research (HEOR)

Travere Therapeutics • San Diego, CA

1d • $246,000 - $332,000 • Remote

About The Position

The Executive Director, Health Economics & Outcomes Research (HEOR) provides strategic leadership for the development and execution of health economics, outcomes research, real-world evidence, patient-reported outcomes, and evidence synthesis strategies across Travere Therapeutics’ nephrology portfolio, including FILSPARI® (sparsentan), civorebrutinib, and future pipeline assets.

The role develops integrated evidence strategies demonstrating the clinical, humanistic, and economic value of Travere’s therapies throughout the product lifecycle. It partners with Medical Affairs, Clinical Development, Market Access, Commercial, Regulatory Affairs, Biostatistics, and other cross-functional teams to identify evidence needs and generate high-quality data supporting scientific exchange, patient access, clinical development, and future value demonstration.

As the senior HEOR expert for the Nephrology Franchise, the Executive Director helps shape long-range evidence strategy for marketed and development-stage assets. The role also oversees external research partners, vendors, budgets, timelines, and project execution, and ensures that all work complies with applicable laws, regulations, industry standards, company policies, and Travere compliance requirements.

Requirements

• Advanced degree in health economics, outcomes research, epidemiology, public health, health services research, pharmacy, medicine, biostatistics, or a related discipline.
• 12 or more years of progressively responsible experience in HEOR, real-world evidence, outcomes research, market access evidence, or related disciplines in biopharmaceutical industry, consulting, academia, or a combination.
• Demonstrated experience developing and executing HEOR and evidence-generation strategies for marketed and/or development-stage assets.
• Strong experience using real-world healthcare data, including claims, EMR/EHR, registries, and other large healthcare databases.
• Experience with health economic modeling, burden-of-illness research, healthcare resource utilization, epidemiology, and observational research.
• Experience with patient-reported outcomes and clinical outcomes assessments, including instrument selection, development, validation, and implementation.
• Experience developing evidence to support payer, reimbursement, and health technology assessment needs.
• Demonstrated record of scientific publications and presentations in HEOR, outcomes research, epidemiology, real-world evidence, or related fields.
• Strong understanding of payer and healthcare decision-maker evidence needs.
• Ability to translate clinical and business questions into rigorous, decision-relevant evidence-generation programs.
• Strong strategic thinking and ability to anticipate evidence needs and connect research priorities to clinical development and product strategy.
• Ability to work effectively across functions and influence senior leaders and cross-functional partners without direct authority.
• Strong scientific judgment, analytical skills, and commitment to research quality and scientific integrity.
• Excellent written and verbal communication skills, including the ability to communicate complex evidence to scientific and non-scientific audiences.
• Strong leadership, organizational, budget management, and vendor management capabilities.
• Ability to manage multiple priorities in a fast-paced and evolving organization.

Nice To Haves

• PhD, PharmD, MD, ScD, DrPH, or equivalent advanced degree.
• Experience in nephrology, rare disease, specialty therapeutics, or progressive chronic diseases.

Responsibilities

• Develop and lead the HEOR and value evidence strategy across the nephrology portfolio, including FILSPARI, civorebrutinib, and future pipeline assets.
• Develop integrated evidence-generation plans addressing clinical, economic, humanistic, and healthcare decision-maker evidence needs throughout the product lifecycle.
• Partner with Clinical Development, Medical Affairs, Market Access, Regulatory, and Biostatistics to identify evidence gaps and integrate HEOR priorities into asset and franchise strategies.
• Lead health economic research, including cost-effectiveness, budget impact, cost-of-illness, healthcare resource utilization, and other analyses.
• Develop and execute real-world evidence studies using claims, electronic medical records, registries, and other healthcare databases.
• Lead the patient-reported outcomes strategy, including selection, development, validation, and appropriate incorporation of fit-for-purpose measures.
• Partner with Clinical Development to incorporate HEOR and outcomes research considerations early in development, including study design, endpoint strategy, evidence gaps, and future access needs.
• Identify opportunities to complement clinical trial evidence with epidemiology, real-world data, health economics, and patient-centered outcomes research.
• Develop evidence to support payer and health technology assessment needs, value dossiers, reimbursement submissions, and other access-related requirements.
• Anticipate future evidence needs and establish research plans supporting new indications, lifecycle opportunities, and future nephrology assets.
• Partner with external research collaborations, data partners, research organizations, and other external experts.
• Develop and oversee HEOR publication plans and disseminate research through peer-reviewed publications, scientific congresses, and other scientific channels.
• Represent Travere externally with HEOR researchers, nephrology experts, academic collaborators, and other scientific stakeholders.
• Serve as an internal subject matter expert in health economics, outcomes research, real-world evidence, and patient-centered outcomes, advising senior leadership and cross-functional teams.
• Manage external vendors, research partners, budgets, timelines, and project execution for HEOR initiatives.
• Ensure activities comply with applicable laws, regulations, industry standards, company policies, and Travere compliance requirements.

Benefits

• Premium health, financial, work-life, and well-being offerings for eligible employees and dependents.
• Wellness and employee support programs.
• Life insurance and disability benefits.
• Retirement plans with employer match.
• Generous paid time off.
• Cash compensation comprising base pay and short-term incentive.
• Long-term incentive compensation in the form of company stock.

What This Job Offers

• Job Type: Full-time
• Career Level: Executive