Senior Manager, DNA Manufacturing Operations & Integration

ModernaTX • Norwood, MA

2d • $130,800 - $209,400 • Hybrid

About The Position

Moderna is hiring a Senior Manager to lead DNA Manufacturing Operations & Integration at its Norwood, Massachusetts campus. The role sits at the intersection of DNA Manufacturing, Cell Bank operations, Operational Excellence, technology transfer, quality, digital capability, and manufacturing performance. The successful candidate will lead a team of Specialists and Senior Specialists and own the continuous improvement agenda for DNA Manufacturing, using operational data, structured problem solving, and cross-functional leadership to identify risks, unlock capacity, strengthen processes, and deliver sustainable improvements.

As a member of the DNA Leadership Team, the Senior Manager will influence organizational priorities, address complex challenges across functional boundaries, and help develop the manufacturing capabilities, culture, and digital practices needed to advance Moderna’s operations. The role partners with groups including MSAT, Quality Assurance, Supply Chain, Digital, CMC Development, and Planning to integrate technical, quality, supply, and business priorities into effective manufacturing execution. It also supports inspection readiness and works with Digital and other partners to explore the use of Generative AI and advanced digital tools within appropriate manufacturing, quality, and data-governance requirements.

The position follows a Monday–Friday schedule, with flexibility potentially required for critical manufacturing activities, technology transfers, regulatory inspections, or significant operational events. Moderna’s working model is 70% in-office. The Norwood work environment is smoke-free, alcohol-free, and drug-free. The salary range is $130,800–$209,400, and the successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or equity award, subject to plan eligibility and performance.

Requirements

• Bachelor’s degree in engineering, science, manufacturing, or another relevant technical discipline, or an equivalent combination of education and relevant industry experience.
• Demonstrated experience in biopharmaceutical manufacturing, technical operations, manufacturing sciences, operational excellence, or a related environment.
• Demonstrated ability to lead and develop people by creating clarity, setting priorities, coaching performance, and building organizational capability.
• Proven ability to influence and lead effectively in a complex matrix organization, including aligning stakeholders outside the individual’s direct authority.
• Demonstrated ownership and successful execution of complex cross-functional projects or programs from problem definition and strategy through implementation and sustained results.
• Experience with GMP manufacturing and quality systems, including change control and other mechanisms for implementing and sustaining changes in a regulated environment.
• Experience supporting technology transfer, manufacturing readiness, process implementation, or other cross-functional technical programs.
• Strong understanding of continuous improvement and Operational Excellence principles, with demonstrated ability to translate them into measurable manufacturing performance improvements.
• Demonstrated ability to use data, trends, and performance indicators to identify problems, establish priorities, and drive decisions and improvement.
• Strong communication, stakeholder management, and organizational leadership skills, including the ability to communicate from the manufacturing floor through senior leadership.
• Ability to operate effectively amid ambiguity, connect technical and business considerations, and take ownership of issues crossing traditional functional boundaries.

Nice To Haves

• Experience supporting regulatory inspections and inspection readiness activities is preferred.

Responsibilities

• Lead, develop, and coach a team of Specialists and Senior Specialists working across DNA and Cell Bank manufacturing processes.
• Own and continuously improve the DNA Manufacturing continuous improvement and Operational Excellence program, including identifying, prioritizing, executing, and realizing benefits from improvement opportunities.
• Lead complex cross-functional initiatives, defining objectives, governance, execution plans, decision-making mechanisms, and delivery accountability.
• Own the strategy and execution of manufacturing change controls associated with area improvements, ensuring changes are planned, assessed, implemented, embedded, and sustained.
• Provide manufacturing leadership and execution support for technology transfers, acting as the Manufacturing representative and coordinating readiness activities and project management across teams.
• Use operational data, performance indicators, manufacturing trends, and operational insights to identify emerging risks, improvement opportunities, capacity constraints, and priorities.
• Establish and evolve operational performance management mechanisms, including dashboards, routine performance reviews, action tracking, and escalation processes.
• Serve as a GMP leader and manufacturing subject matter expert, supporting investigations, operational events, risk assessments, change implementation, and other quality system activities.
• Partner with MSAT, Quality Assurance, Supply Chain, Digital, CMC Development, Planning, and other stakeholders to integrate technical, quality, supply, and business priorities into manufacturing execution.
• Support ongoing inspection readiness by ensuring relevant teams, processes, documentation, change activity, and improvements are prepared for regulatory inspections.
• Build organizational capability in continuous improvement, structured problem solving, project execution, data-driven decision making, and change management.
• Contribute as a member of the DNA Leadership Team to strategy, organizational priorities, operational performance, workforce engagement, and resolution of broader DNA Operations issues.
• Foster a positive, collaborative, accountable, and inclusive culture, serving as a visible leader and role model and supporting organizational performance and well-being.
• Act as a trusted advisor and problem solver for DNA Operations leadership, taking ownership of complex or ambiguous challenges across functional boundaries.
• Work with Digital and cross-functional partners to explore Generative AI and other advanced digital tools for operational insights, problem solving, knowledge access, performance management, and decision making, within applicable manufacturing, quality, and data-governance requirements.
• Drive results through the team’s execution of complex initiatives, sustainable improvements, change management, technology transfers, proactive use of data, and stronger DNA Manufacturing capability and performance.

Benefits

• Competitive healthcare and voluntary benefit programs.
• Well-being resources, including fitness, mindfulness, and mental health support.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
• Savings and investment programs.
• Location-specific perks and extras.
• Potential eligibility for an annual discretionary bonus, other incentive compensation, or an equity award, subject to plan eligibility criteria and individual performance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior