Senior Manager, DNA Manufacturing Operations & Integration

Moderna • Norwood, MA

3d • $130,800 - $209,400 • Hybrid

About The Position

Moderna is hiring a Senior Manager to lead DNA Manufacturing operations and integration at its Norwood, Massachusetts campus. The role sits at the intersection of DNA Manufacturing, Cell Bank operations, operational excellence, technology transfer, quality, digital capability, and manufacturing performance. The position leads a team and owns the continuous improvement agenda, using operational data, structured problem solving, and cross-functional leadership to identify risks, improve capacity and processes, and deliver sustainable results.

As a member of the DNA Leadership Team, the Senior Manager will influence broader organizational priorities and help build manufacturing capabilities, culture, and digital ways of working. The role partners across Manufacturing Science & Technology, Quality Assurance, Supply Chain, Digital, CMC Development, Planning, and other functions to align technical, quality, supply, and business priorities. It also supports GMP operations, change control, technology transfers, inspection readiness, and the effective use of advanced digital tools within manufacturing, quality, and data-governance requirements.

The role is based within a 70/30 in-office work model. The typical schedule is Monday through Friday, with flexibility potentially required for critical manufacturing activities, technology transfers, regulatory inspections, or significant operational events. Moderna describes its workplace as smoke-free, alcohol-free, and drug-free.

Requirements

• Bachelor’s degree in engineering, science, manufacturing, or another relevant technical discipline, or an equivalent combination of education and relevant industry experience.
• Demonstrated experience in biopharmaceutical manufacturing, technical operations, manufacturing sciences, operational excellence, or a related environment.
• Ability to lead and develop people by creating clarity, setting priorities, coaching performance, and building organizational capability.
• Ability to influence and lead in a complex matrix organization, including when execution requires alignment of stakeholders outside the individual’s direct authority.
• Proven ownership and successful execution of complex cross-functional projects or programs from problem definition and strategy through implementation and sustained results.
• Experience with GMP manufacturing and quality systems, including change control and mechanisms for implementing and sustaining changes in a regulated environment.
• Experience supporting technology transfer, manufacturing readiness, process implementation, or other cross-functional technical programs.
• Strong understanding of continuous improvement and operational excellence principles, with the ability to translate them into measurable manufacturing performance improvements.
• Ability to use data, trends, and performance indicators to identify problems, set priorities, and drive decisions and improvement.
• Strong communication, stakeholder-management, and organizational-leadership skills, including the ability to communicate from the manufacturing floor through senior leadership.
• Ability to operate effectively in ambiguity, connect technical and business considerations, and own problems that cross traditional functional boundaries.

Nice To Haves

• Experience supporting regulatory inspections and inspection-readiness activities.

Responsibilities

• Lead, develop, and coach Specialists and Senior Specialists working across DNA and Cell Bank manufacturing processes.
• Own and continuously improve the DNA Manufacturing continuous improvement and Operational Excellence program, including identifying, prioritizing, executing, and realizing the benefits of improvement opportunities.
• Lead complex cross-functional initiatives by defining objectives, governance, execution plans, decision-making mechanisms, and accountability.
• Own the strategy and execution of manufacturing change controls for area improvements, ensuring changes are planned, assessed, implemented, embedded, and sustained.
• Provide manufacturing leadership and execution support for technology transfers, including readiness activities and cross-functional project management.
• Use operational data, performance indicators, trends, and insights to identify risks, opportunities, capacity constraints, and priorities for DNA Operations.
• Establish and evolve performance-management mechanisms, including dashboards, routine reviews, action tracking, and escalation processes.
• Serve as a GMP leader and manufacturing subject matter expert, supporting investigations, operational events, risk assessments, change implementation, and other quality-system activities.
• Partner with MSAT, Quality Assurance, Supply Chain, Digital, CMC Development, Planning, and other stakeholders to coordinate manufacturing execution.
• Support inspection readiness for the team, processes, documentation, change activity, and improvements within the role’s scope.
• Build organizational capability in continuous improvement, structured problem solving, project execution, data-driven decision making, and change management.
• Contribute to DNA Leadership Team strategy, organizational priorities, operational performance, workforce engagement, and resolution of broader DNA Operations issues.
• Foster a positive, collaborative, accountable, and inclusive culture, serving as a visible leader and role model and supporting organizational performance and well-being.
• Advise DNA Operations leadership and take ownership of complex or ambiguous challenges across functional and organizational boundaries.
• Work with Digital and cross-functional partners to explore the use of Generative AI and other advanced digital tools for operational insights, problem solving, knowledge access, performance management, and decision making within applicable manufacturing, quality, and data-governance requirements.
• Drive team execution of complex initiatives, sustainable improvements, change management, technology transfers, proactive data use, and ongoing improvement of DNA Manufacturing capability and performance.

Benefits

• Competitive healthcare and voluntary benefit programs.
• Access to fitness, mindfulness, and mental health support.
• Family planning benefits, including fertility, adoption, and surrogacy support.
• Paid time off, including vacation, volunteer days, sabbatical, global recharge days, and a discretionary year-end shutdown.
• Savings and investment programs to help employees plan for the future.
• Location-specific perks and extras.
• The successful candidate may be eligible for an annual discretionary bonus, other incentive compensation, or an equity award, subject to plan eligibility criteria and individual performance.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior