Senior Global Brand Director panKRAS

AstraZeneca • Gaithersburg, MD

9h

About The Position

The Senior Director, Global Commercial, panKRAS will lead the global commercial strategy for AstraZeneca’s clinical-stage, oral, multi-target KRAS inhibitor, a priority asset within the GI Oncology portfolio. The role will shape the asset’s commercial potential from an early stage, providing strategic and commercial input to development priorities, evidence generation and investment decisions. It will translate patient, customer, market and competitive insights into choices on indication prioritisation, patient populations, target product profile, differentiation and sequencing, and establish the foundation for future launch excellence, including preparations for the lead indication.

As part of the Global IO Commercial Franchise Team, the role works closely with Clinical Development, Global Medical Affairs, Regulatory Affairs, Diagnostics, Pricing and Market Access, Global Analytics & Insights, Digital, Corporate Affairs, regional and country teams, and other partners. It is accountable for differentiated strategy and positioning, deep customer and market insights, commercial input to development and investment decisions, market-shaping programmes, and commercial planning through launch and beyond. The role also represents Global Commercial in cross-functional teams and governance forums to ensure development choices reflect future patient, customer and market needs.

The position leads global brand strategy and planning; launch strategy, readiness and execution across priority markets; agency and vendor relationships; brand budgets, forecasts and resource allocation; performance measurement; and senior leadership updates. It proactively manages strategic, operational, regulatory and reputational risks and ensures activities comply with applicable policy, legal, regulatory and industry requirements.

Requirements

• Bachelor’s degree in a relevant field.
• 10+ years’ experience in the pharmaceutical and/or healthcare industry, with experience in one or more of brand marketing, sales, market research/analytics or strategic planning.
• Relevant experience in pharmaceutical development and commercialisation, including strong oncology commercial experience.
• Proven pre-launch and launch excellence, including creating and executing global brand strategies and campaigns.
• Strong strategic marketing, customer insight, forecasting, market research, competitive analysis and business-case skills.
• Strong clinical and scientific acumen and the ability to translate complex evidence into clear commercial choices.
• Demonstrated success leading cross-functional teams in a global matrix and influencing laterally and vertically.
• Strong business and financial acumen, including budget and agency management.
• Exceptional written, verbal and presentation skills, with the ability to communicate clearly to senior leaders and diverse markets.
• Enterprise mindset, high ethical standards, personal integrity, urgency and ability to deliver with a high degree of autonomy.

Nice To Haves

• GI Oncology, pancreatic or colorectal cancer, or biomarker-driven therapy experience.
• Advanced degree in business, science or a related field; MBA preferred.
• Sales, customer-facing or market access experience.
• Formal people-management experience.
• Experience supporting late-stage development, Phase III investment decisions or lifecycle strategy.

Responsibilities

• Set and communicate a differentiated, long-term global brand strategy aligned with GI tumour strategy and broader Oncology priorities.
• Lead annual strategic and operational planning, including positioning, segmentation, customer strategy, value proposition, target market selection and lifecycle priorities.
• Generate customer, patient, market and competitive insights and translate them into choices that address unmet need and maximise value.
• Provide commercial and strategic input to development priorities, including indication and patient-segment prioritisation, target product profile, evidence-generation needs, clinical development trade-offs and investment choices.
• Develop revenue forecasts and business cases informed by insights and commercial judgement.
• Represent Global Commercial in product team, development and investment forums, contributing to evidence-generation, clinical development, stage-gate and Phase III investment decisions.
• Lead global launch strategy, readiness and execution across priority markets, with milestones, decision points and performance measures.
• Engage regional and country teams early, incorporate market feedback, and establish ways to share learning and accelerate adoption of best practice.
• Lead agency and vendor relationships, ensuring quality, pace, compliance, value and effective use of resources.
• Manage global brand budgets, forecasts and resource allocation with clear prioritisation and financial discipline.
• Define a focused performance framework and use leading and lagging measures to identify gaps, risks and opportunities.
• Provide high-quality brand and business updates to senior leadership, generating clear decisions and follow-through.
• Proactively identify and manage strategic, operational, regulatory and reputational risks and ensure compliance with policy, legal, regulatory and industry requirements.
• Lead cross-functional work and represent commercial perspectives in relevant governance forums.

Benefits

• Short-term incentive bonus opportunity.
• Eligibility to participate in the equity-based long-term incentive program for salaried roles.
• Retirement contribution for hourly roles.
• Commission payment eligibility for sales roles.
• Overtime pay for hourly and salaried non-exempt employees working qualifying overtime hours.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior