Senior Engineer, Small Molecule Process Development and Manufacturing

Biogen•Cambridge, MA

About The Position

We are seeking a highly motivated and creative Chemical Engineer to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to develop robust processes for the synthesis of a wide range of assets across various modalities. As a Senior Engineer, you will gain experience in early to late-phase drug development and exposure to designing and developing manufacturing processes for clinical and commercial therapeutics. You will collaborate with a team of organic chemists and chemical engineers in designing innovative processes that supply new medicines to patients.

Requirements

Ph.D. with 5+ years of relevant experience.
M.S. with 6+ years of relevant experience in pharmaceutical or biotech settings.
BS with 7+ years of relevant experience in pharmaceutical or biotech settings.
Strong background in pharmaceutical chemical engineering, including crystallization techniques, process characterization, process safety, and tech transfer protocols.
Experience in crystallization of APIs and familiarity with analytical tools and purification techniques.
Ability to work both independently and collaboratively.
Good communication skills and the desire to work in a collaborative team environment.

Nice To Haves

Experience with process characterization, crystallization techniques, drug substance form control, and familiarity with process safety protocols.
Demonstrated problem-solving skills in pharmaceutical chemical engineering.

Responsibilities

Collaborate with development and manufacturing teams to design and conduct laboratory experiments aimed at optimizing and characterizing processes.
Design and execute experiments to advance the portfolio, analyzing and sharing data to implement efficient and robust chemical processes.
Manage key laboratory instrumentation
Develop fundamental process knowledge for transitioning processes from lab scale to manufacturing partners.
Collaborate with Process Chemistry, Analytical Chemistry, Solid Form, and Separations colleagues to support clinical material supply and regulatory filings.
Write research reports, present data in team meetings, and engage in CMC activities, including authoring CMC sections of INDs.
Interact with Contract Research Organizations as project needs evolve.
Initiate innovative research projects to improve process understanding and control.
Mentor and guide earlier career team members.

Benefits

Medical, Dental, Vision, & Life insurances
Fitness & Wellness programs including a fitness reimbursement
Short- and Long-Term Disability insurance
A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
Paid Maternity and Parental Leave benefit
401(k) program participation with company matched contributions
Employee stock purchase plan
Tuition reimbursement of up to $10,000 per calendar year
Employee Resource Groups participation