Associate Director of Engineering, Small Molecule Process Development and Manufacturing

Biogen•Cambridge, MA

About The Position

We are seeking a highly motivated and creative Chemical Engineer to join our Small Molecule Chemical Development team. This position provides an exciting opportunity to lead and mentor scientific and engineering teams in the development of robust processes for the synthesis of a wide range of Small Molecules across various modalities. This Associate Director of Engineering position provides experiences in early phase to late phase drug development and exposure to the design and development of manufacturing processes for clinical and commercial therapeutics.

Requirements

Ph.D. with 6+ years of relevant experience in pharmaceutical or biotech settings.
M.S. with 8+ years of relevant experience in pharmaceutical or biotech settings.
BS with 10+ years of relevant experience in pharmaceutical or biotech settings
Strong background in the theory and practice of pharmaceutical chemical engineering, including demonstrated understanding of crystallization techniques, experience with process characterization, familiarity with process safety and tech transfer protocols, and good problem solving skills
Good communication skills and the desire to work in a collaborative team environment

Nice To Haves

Experience in crystallization and isolation of APIs across several modalities is preferred, as well as familiarity with analytical tools and various purification techniques.

Responsibilities

Lead collaborative development for manufacturing teams to design and conduct laboratory experiments to optimize and characterize the processes of Biogen assets, with an emphasis on improvement in process understanding, robustness, and productivity
Design and lead experimental planning to advance the Biogen portfolio.
Responsible for leading project teams towards the implementation of safe, efficient and robust chemical processes of Biogen drug candidates
Responsible for overseeing the management of key laboratory and kilo lab instrumentation
Develop the fundamental process knowledge needed to support the transition of chemical and biochemical processes from laboratory scale to manufacturing partners
Collaborate with our Process Chemistry, Analytical Chemistry, Solid Form, Oligo, and Separations colleagues to develop the knowledge and controls needed for the supply of clinical materials and characterization of the process to support regulatory filings
Communicate project team research results effectively by in reports and discussions in team meetings, including engagement in CMC activities including authoring CMC section of INDs
Interact with Contract Research Organizations as project needs evolve, which may include travel
Initiate innovative research projects to improve fundamental understanding and control of Biogen processes
Expand on your external presence professionally representing Biogen externally in consortia and conferences
Engage, mentor, and prepare our future chemical engineering leaders

Benefits

Medical, Dental, Vision, & Life insurances
Fitness & Wellness programs including a fitness reimbursement
Short- and Long-Term Disability insurance
A minimum of 15 days of paid vacation and an additional end-of-year shutdown time off (Dec 26-Dec 31)
Up to 12 company paid holidays + 3 paid days off for Personal Significance
80 hours of sick time per calendar year
Paid Maternity and Parental Leave benefit
401(k) program participation with company matched contributions
Employee stock purchase plan
Tuition reimbursement of up to $10,000 per calendar year
Employee Resource Groups participation