Senior Director, Value and Access

Madrigal Pharmaceuticals•Conshohocken, PA

1d•$263,000 - $321,000•Hybrid

About The Position

The Senior Director, Value and Access will serve as a strategic leader within Madrigal Pharmaceuticals, driving payer value communication, access strategy, and innovation across the U.S. payer landscape for therapies in Metabolic Dysfunction-associated Steatohepatitis (MASH). This role integrates traditional payer marketing responsibilities with forward-looking horizon scanning and payer innovation to ensure both near-term access success and long-term market leadership. The Senior Director is accountable for developing and executing strategic value communication platforms that clearly articulate the differentiated value of Rezdiffra to Commercial, Medicare, and Medicaid payers. This includes the creation of tailored tools and resources—payer value decks, cost-impact claims, objection handlers, and training programs—that empower field teams (NADs, RADs, KADs) to effectively communicate Madrigal's clinical and economic value story. Simultaneously, the role is responsible for proactively identifying, evaluating, and responding to emerging payer trends, competitive threats (e.g., GLP-1s, FGF21s, etc.), evolving value frameworks, and innovative reimbursement models. The Senior Director will lead initiatives to develop and pilot value-based agreements and risk-sharing strategies in collaboration with cross-functional stakeholders. Through integration of payer marketing excellence and strategic foresight, the Senior Director will ensure Madrigal maintains its first-mover advantage in MASH while preparing the organization for future payer dynamics. This position plays a critical role in shaping both current access execution and future access innovation, in alignment with brand, HEOR, and policy teams.

Requirements

Proven ability to synthesize clinical, economic, and market data into compelling payer narratives.
Strong understanding of U.S. payer dynamics, field access operations, and the interplay between brand and market access strategy.
Experience collaborating with commercial and field teams to drive access pull-through and payer engagement.
Proven ability to lead cross-functional teams and manage external partners/vendors.
Strong communication skills, with experience crafting messages for both internal field teams and external payer audiences.
Detail-oriented with strong project management skills and the ability to execute against tight timelines.
Strategic mindset with a proactive approach to addressing market access challenges and opportunities.
Advanced degree preferred (PharmD, MPH, MHA, PhD, or MBA).
Minimum 15+ years of experience in the pharmaceutical/biotech industry, with at least 5 years in payer value communications or market access.
Track record of developing impactful payer materials in support of field execution.
Therapeutic experience in metabolic, hepatic, or cardiovascular disease strongly preferred.
Experience in adjacent functions such as Market Access Strategy, Deal Evaluation, Payer Account Management, etc. highly preferred.

Responsibilities

Develop and execute comprehensive value communication strategies to drive payer coverage, reimbursement, and pull-through across Commercial, Medicare, and Medicaid markets.
Lead the development of payer value stories and other messaging resources supported by clinical evidence and health economics data to demonstrate the differentiated value of Madrigal’s therapies.
Integrate brand strategy into payer messaging by partnering closely with Brand Marketing to ensure alignment across patient, HCP, and payer communication channels.
Tailor value narratives to specific payer archetypes and coverage scenarios, anticipating access barriers and articulating clear justifications for formulary inclusion.
Continuously refine the overall value proposition based on evolving payer needs, policy shifts, and competitor developments.
Collaborate with HEOR and Medical to ensure alignment of payer messaging with evidence generation and scientific narratives.
Work with the commercial team to embed access and affordability messaging into HCP engagement plans and marketing tactics.
Design omnichannel content strategies that reinforce the product value proposition via digital, email, portal, journal, and conference-based touchpoints.
Create payer engagement materials for National Access Directors (NADs), Regional Access Directors (RADs), and Key Account Directors (KADs), including objection handlers, FAQs, and scenario-based field tools.
Develop and lead training initiatives to ensure NADs, RADs, and KADs are confident in communicating the clinical and economic value of Madrigal’s therapies.
Anticipate and interpret trends in U.S. payer evidence requirements.
Support the development of strategies that adapt Madrigal’s value communication in response to new competitive entrants and payer management approaches.
Serve as a strategic thought partner in identifying emerging threats and opportunities in value demonstration.
Lead proactive horizon scanning initiatives to monitor evolving payer evidence requirements, value frameworks, and reimbursement models (e.g., ICER, CMS innovation).
Analyze competitor market access strategies and pipeline disruptions (e.g., GLP-1s, FGF21s) to inform defensive positioning.
Design and pilot innovative payer engagement approaches including value-based agreements, with tailored constructs per payer archetype.
Advise internal stakeholders on forward-looking risks and strategic opportunities to sustain access leadership.
Collaborate with Market Access, Pricing, and Trade teams to ensure consistency and synergy across all access-related strategies.
Contribute insights and evidence inputs to strategic planning and pricing committee discussions as needed.
Ensure all payer-facing materials are accurate, fair-balanced, and compliant with legal, regulatory, and industry standards.
Collaborate with Legal, Regulatory, and Compliance teams to review and approve value communication content.