Senior Director, Global Tuberculosis

Clinton Health Access Initiative • or CHAI Program Country,

5d

About The Position

The Clinton Health Access Initiative, Inc. (CHAI) is a global health organization committed to saving lives and reducing the burden of disease in low- and middle-income countries. CHAI works with governments and the private sector to create and sustain high-quality health systems. The Global TB Program aims to close critical gaps across the TB care cascade by focusing on screening and diagnosis, treatment and prevention, and market shaping. The program currently operates in 13 countries in Africa and Asia, providing strategic direction, technical leadership, and coordination. This role is for a Senior Director who will serve as CHAI's most senior voice on TB, setting a clear programmatic vision, articulating it compellingly, and leading the translation of strategy into action. The Senior Director will report to the Vice President, HIV, Hepatitis and TB, and will be responsible for shaping a portfolio that spans community-based prevention pilots, diagnostic technology introduction, market shaping interventions, and operational research across multiple countries. The ideal candidate will have a rigorous, quantitative approach to resource allocation and a track record of delivering sustainable public health impact in low- and middle-income countries.

Requirements

• 10+ years of progressive experience in global health, development, philanthropy, or a related field, with increasing levels of responsibility and leadership.
• Strong grounding in economics, cost-effectiveness analysis, or quantitative approaches to resource allocation, with the ability to build, interrogate, and explain impact models.
• Fluency in how evidence-driven funders evaluate opportunities and make decisions, with the credibility to engage them as a peer.
• Demonstrated success leading global or multi-country programs, or advising governments or directing funding for them, with a clear track record of contributing to measurable public health impact in low- and middle-income countries.
• Outstanding communicator who can distil complex technical and strategic issues into clear, persuasive narratives for varied audiences, and who uses communication deliberately to build consensus, inspire action, and sustain momentum behind a shared vision.
• Strong resource mobilization experience, including leading successful proposal development and donor engagement for large, multi-year grants.
• Excellent project and people management skills, including managing senior technical staff and designing and managing cross-functional teams spanning multiple geographies and time zones.
• Demonstrated high bar for quality, analytical rigour, and attention to detail in programmatic outputs and strategic deliverables.
• Track record of building and managing relationships with senior government officials, multilateral organizations, and major institutional donors, with demonstrated ability to align diverse stakeholders around a common agenda and maintain productive partnerships even when organizational interests do not fully overlap.
• Entrepreneurial mindset, with the ability to identify and pursue new opportunities, work independently, and drive initiatives forward in fast-paced, limited-structure environments.
• Ability and willingness to travel internationally 25 to 30 percent of the time.

Nice To Haves

• Experience working at, with, or for evidence-focused or effective giving-aligned funders, or in roles where cost-effectiveness analysis drove resource allocation decisions.
• Knowledge of tuberculosis, including TB epidemiology, diagnostics, therapeutics, and the global TB policy and financing architecture.
• Prior experience working with or within national TB programs, the Stop TB Partnership, the Global Fund, Gates, or Unitaid.
• Experience in market shaping, health commodity procurement, or access-to-medicines initiatives in a global health context.
• Experience living and working in sub-Saharan Africa, South or Southeast Asia, or other high-TB-burden regions.
• Advanced degree in economics, public policy, public health, management, science, or other relevant fields.

Responsibilities

• Define and communicate a bold strategic direction for CHAI's global TB portfolio, translating organizational priorities, donor expectations, and the evolving needs of high-burden countries into a coherent vision.
• Scan the horizon for shifts in TB financing, epidemiology, policy, and the diagnostic and therapeutic pipeline; position CHAI to respond proactively and shape the conversation.
• Make disciplined strategic choices about where CHAI should focus, including decisions to scale, pivot, or wind down workstreams based on evidence of impact per dollar, counterfactual value, and changing conditions.
• Develop multi-year programmatic plans, budgets, and performance management systems that drive accountability and continuous improvement across the portfolio.
• Champion the translation of evidence and operational learning into scalable, government-led program models.
• Orient the program at every stage toward government ownership, from design through financing and scale-up, so that impact endures beyond CHAI's engagement.
• Lead development and execution of CHAI's TB resource mobilization strategy, sustaining and growing support from long-standing institutional donors while building a significant new base of support from evidence-driven philanthropy.
• Manage major donor relationships and program finances, including with the Global Fund, Gates Foundation, Unitaid, FCDO, and GiveWell, ensuring high-quality reporting, proactive risk management, and disciplined deployment of resources.
• Build relationships with funders who prioritize cost-effectiveness, including foundations, individual philanthropists, and pooled funds associated with the effective giving community.
• Make the case for TB investment in the terms these funders use: cost per death or disability-adjusted life year (DALY) averted, counterfactual impact, room for more funding, and the quality of the underlying evidence.
• Engage directly with funders' research and grant making staff, responding to detailed questions about assumptions, uncertainty, and track record, and using that scrutiny to strengthen the program.
• Identify and pursue non-traditional funding opportunities, positioning CHAI's TB work within broader global health and development agendas, including the growing interest in AI-enabled health solutions.
• Set the intellectual agenda for CHAI's TB work: define the questions the organization should be asking, identify where conventional approaches are falling short, and push the team to develop stronger answers.
• Own the TB program's impact model: the cost-effectiveness estimates, assumptions, and uncertainty behind CHAI's investment case. Revise it as evidence changes and defend it with funders, partners, and governments.
• Ensure country and regional teams receive strong technical guidance on complex programmatic, policy, and scientific questions spanning diagnostics, treatment, prevention, and service delivery, working closely with the program's technical Directors.
• Drive CHAI's TB learning and research agenda, including operational research, impact evaluations, cost-effectiveness analyses, and data-driven refinements to program design, ensuring that findings are translated into action.
• Ensure CHAI stays ahead of the frontier of TB science and innovation, so it can move quickly as new screening, diagnostic, and treatment tools emerge.
• Represent CHAI at the highest levels of the global TB community, from ministerial meetings to donor convenings to technical forums, and in philanthropic settings where TB competes with other causes for attention and funding.
• Actively shape how the global community prioritizes, funds, and organizes the TB response, bringing evidence and operational insight to bear on policy and investment decisions.
• Strengthen CHAI's positioning as a trusted partner and thought leader in the TB ecosystem, known for evidence-informed approaches and a commitment to practical, scalable solutions.
• Build and sustain trusted relationships across a diverse ecosystem of multilateral organizations (WHO, the Global Fund, Stop TB Partnership), bilateral donors, academic institutions, suppliers, implementing partners, and civil society, understanding each partner's priorities and finding productive ways to collaborate toward shared objectives.
• Navigate a multi-stakeholder landscape with diplomacy and strategic clarity, identifying opportunities for collective action while ensuring CHAI's distinctive contributions are well understood and valued.
• Contribute to shaping the global policy environment for TB, including regulatory pathways, normative guidance, and investment frameworks.
• Lead, develop, and grow a diverse, high-performing team, strengthening the team's capabilities over time to keep pace with the program's evolving ambitions.
• Provide direct management and mentorship to senior team members, including the program's two technical Directors and other managers of people, investing in their professional development and enabling them to lead their respective portfolios with confidence and autonomy.
• Foster a team culture grounded in intellectual rigour, collaboration, accountability, and continuous learning.
• Own the TB program's results. Be accountable not only for how the work is managed but for what it achieves: reductions in undiagnosed TB, expanded preventive treatment coverage, sustainable improvements in how countries detect, treat, and prevent the disease, and a clear account of what each dollar invested delivers.
• Work in close partnership with CHAI country directors and country-based staff, recognizing that the strongest global strategies are built on the insights, relationships, and operational realities that country teams bring.
• Collaborate closely with leaders across CHAI's HIV, Diagnostics, Markets, Health Systems, and AI programs to identify synergies, share learning, and pursue integrated approaches where they strengthen impact.
• Contribute to organization-wide initiatives that strengthen CHAI's culture, effectiveness, and ability to adapt in a rapidly changing global health landscape.

Benefits

• CHAI is an Equal Opportunity Employer, and is committed to providing an environment of fairness, and mutual respect where all applicants have access to equal employment opportunities.
• CHAI values diversity and inclusion, and recognizes that our mission is best advanced by the leadership and contributions of people with diverse experience, backgrounds, and culture.

What This Job Offers

• Job Type: Full-time
• Career Level: Senior