Senior Director, Clinical & Commercial Supply Chain
About The Position
Remix Therapeutics is a clinical-stage biopharmaceutical company developing medicines that modulate RNA splicing. The Senior Director, Clinical and Commercial Supply Chain will lead end-to-end supply planning and operational launch readiness for Remix’s first commercial product, ensuring product availability, compliant distribution, and robust performance management. Reporting to the Vice President, Technical Operations, this highly visible leadership role owns clinical and commercial supply strategies and translates demand forecasts into actionable plans. The role works cross-functionally with Quality, CMC, Clinical, Commercial, Regulatory, Accounting/Finance, and IT, as well as external manufacturing, packaging, labeling, logistics, and storage partners. The position requires a hands-on, autonomous leader comfortable managing complex supply chains in a fast-paced, evolving environment.
Requirements
- BA/BS in Supply Chain, Engineering, or Life Sciences.
- 15+ years of experience in biotech/pharma supply chain, including 10+ years of commercial and/or late-stage launch readiness experience.
- Ability and willingness to be a hands-on leader and step into a visible role quickly with minimal supervision.
- Experience in a highly outsourced biotechnology operating model.
- Demonstrated experience managing external manufacturing and supply partners.
- Strong understanding of GMP/GDP, regulatory timing impacts on supply, and global distribution logistics.
- Advanced planning and analytics skills, including Excel and/or supply planning tools.
- Strong cross-functional leadership and communication skills.
- Comfort operating amid ambiguity and building processes from the ground up.
- Team-oriented approach, integrity, commitment to quality, and ability to think critically and creatively in a fast-paced, changing environment.
- Proficiency in Microsoft Office Suite and experience with collaborative platforms such as SharePoint or Box, and NetSuite inventory systems.
- Willingness and ability to travel domestically and internationally as needed.
Nice To Haves
- Advanced degree preferred.
Responsibilities
- Own clinical supply strategy to ensure continuous supply for all portfolio clinical programs.
- Own commercial supply strategy for the first commercial product, including launch readiness, demand planning and forecasting, and CMO management.
- Develop and maintain integrated demand and supply plans, CMO manufacturing schedules, capacity models, inventory strategies, and scenario analyses.
- Lead the S&OP cadence, including monthly supply reviews, risk and opportunity assessments, mitigation actions, and executive-ready reporting.
- Lead end-to-end, GxP- and SOX-compliant inventory management across clinical and commercial supply, including inventory policies, reconciliation, cycle-counting oversight, expiry tracking, and alignment with demand and production plans.
- Manage external network execution and align campaign plans and batch execution with forecasts and contractual commitments.
- Partner with Finance and Accounting on reconciliations, chargebacks, rebates, and related activities.
- Oversee commercial packaging readiness, including secondary packaging and labeling, serialization strategy and execution, artwork lifecycle coordination, shipping lane validation, controlled shipping conditions, and exception management.
- Serve as the primary contact for commercial packaging, labeling, logistics, and storage vendors, and develop a governance process for managing them.
- Build and monitor KPIs and dashboards for service level, plan adherence, capacity utilization, and inventory health; lead continuous improvement of planning tools and processes.
- Partner with Quality, Regulatory, and CMC to ensure GxP-compliant release and distribution readiness and alignment with registration timelines.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
