Senior Associate Scientist
Bristol Myers Squibb•San Diego, CA
•Onsite
About The Position
The Protein Homeostasis Thematic Research Center at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.
Requirements
- Bachelor’s Degree 4+ years of academic and / or industry experience
- Or Master’s Degree 2+ years of academic and / or industry experience
Nice To Haves
- Experience developing high-throughput, multiplexable functional screening platforms, including generation and maintenance of 500+ solid tumor and hematological engineered cell line models
- Skilled in methodologies for engineered cell line validation, including lentiviral transduction, flow cytometry, STR profiling, western blot, and targeted PCR
- Demonstrated ability to perform NGS-based amplicon sequencing assays and drive platform improvements to increase efficiency
- Experience supporting oncology drug discovery pipelines through design and execution of cell-based assays with a focus on genetic-perturbation strategies to interrogate novel therapeutic targets
- Ability to effectively communicate scientific findings to cross-functional teams
- Proficiency using scientific data analysis programs including GraphPad Prism, FlowJo (or Python-based flow analysis), Microsoft Excel and PowerPoint, GeneMapper, TapeStation Analysis Software
Responsibilities
- Designs and executes experiments based on cell and molecular biology protocols
- Analyzes and interprets experimental data
- Prepares and presents experimental results to project team leaders
- Works within established procedures to perform large-scale cell-based assays
- Actively participates in troubleshooting to implement data-driven solutions to cell engineering challenges and optimize NGS library protocols to utilize new technologies
- Coordinates activities with other team members to achieve results
Benefits
- Medical, pharmacy, dental, and vision care
- BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP)
- 401(k) plan
- short- and long-term disability
- life insurance
- accident insurance
- supplemental health insurance
- business travel protection
- personal liability protection
- identity theft benefit
- legal support
- survivor support
- flexible time off (unlimited, with manager approval)
- 11 paid national holidays
- 160 hours annual paid vacation for new hires with manager approval
- 3 optional holidays
- unlimited paid sick time
- up to 2 paid volunteer days per year
- summer hours flexibility
- leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs
- annual Global Shutdown between Christmas and New Years Day
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What This Job Offers
Job Type
Full-time
Career Level
Senior
