Senior Associate Scientist
Bristol Myers Squibb•San Diego, CA
•Onsite
About The Position
The Protein Homeostasis Thematic Research Center at BMS is a fundamental Oncology research engine delivering oncology and hematology therapeutics to patients. The TRC has a major focus on exploiting BMS’ expertise in protein degradation to discover and develop therapies aimed at tumor intrinsic vulnerabilities and mechanisms of resistance to existing cancer therapeutics. This focus on protein degradation allows us to attack protein classes that were previously deemed undruggable.
Requirements
- Bachelor’s Degree 4+ years of academic and / or industry experience OR Master’s Degree 2+ years of academic and / or industry experience
- Advanced cell culture skills with hands-on experience in cell engineering and gene editing, including CRISPR, RNAi, gene overexpression, and lentiviral transduction
- Expertise in cell-based assays and high-throughput screening (HTS), including cell proliferation, cell cycle, apoptosis, 3D sphere formation, and senescence
- Experience with molecular and cellular biology and biochemistry techniques, such as qPCR, immunofluorescence, Western blot, ELISA, MSD, and FACS
- Experience in MOA studies using integrative multi-omic approaches, including preparation of samples for proteomic, transcriptomic, and chromatin-binding studies
- Familiarity with key aspects of SAR support using a variety of biological assays
- Ability to design, plan, and execute scientific experiments with moderate supervision
- Strong attention to detail and ability to follow laboratory procedures and execute bench experiments
- Proficiency in data analysis and visualization tools, including MS Office and GraphPad Prism
- Highly motivated, innovative, and able to multitask effectively in a fast-paced, dynamic team environment
- Strong communication, collaboration, and organizational skills
- Ability to deliver high-quality data in a timely and well-organized manner
Nice To Haves
- Proven publication record as a major contributor or author is a plus
Responsibilities
- Develop and execute a range of assays to support structure–activity relationship (SAR) studies
- Design and implement biochemical and cell-based assays to enable target validation and mechanism-of-action (MOA) investigations
- Analyze, interpret, and present data in team meetings and potentially cross-functional forums
- Collaborate effectively with cross-functional teams to drive project progress and achieve program objectives
Benefits
- Medical, pharmacy, dental, and vision care
- BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP)
- 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support
- flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees))
- 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays
- unlimited paid sick time
- up to 2 paid volunteer days per year
- summer hours flexibility
- leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs
- an annual Global Shutdown between Christmas and New Years Day
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What This Job Offers
Job Type
Full-time
Career Level
Senior
