Senior Associate Scientist LNP Analytical Testing - Cambridge MA
About The Position
The Senior Associate Scientist performs routine analytical testing to support research, process development, stability, and quality control activities. The role executes and documents laboratory experiments in accordance with established SOPs, protocols, and Good Laboratory Practice (GLP) standards; analyzes and summarizes experimental data; and prepares laboratory reports and technical summaries. The position also maintains laboratory equipment, prepares reagents and standards, manages consumables, supports method development and optimization, and collaborates with research, process development, and formulation teams. The role is on-site in Cambridge, Massachusetts.
Requirements
- Bachelor's degree in Biochemistry, Chemistry, Biology, Pharmaceutical Sciences, or a related scientific discipline.
- 1–5 years of hands-on laboratory experience; experience involving RNA and/or lipid nanoparticles (LNPs) is preferred, including academic research, internships, or industry roles.
- Proficiency with ELISA, Western blotting, cell-based assays, UV-Vis spectroscopy, or qPCR.
- Proficiency with HPLC operations, including method execution, column management, and chromatography data systems such as Empower, OpenLabs, or Chromeleon.
- Ability to manage multiple priorities in a fast-paced environment while maintaining accuracy and attention to detail.
- Ability to analyze data and present results to a team and the larger research community.
- Familiarity with ICH guidelines, GLP/GMP principles, and regulatory submission requirements.
- Experience with bioanalytical method validation, such as validation under FDA or EMA guidelines.
- Working knowledge of statistical analysis tools such as GraphPad Prism, JMP, or Excel-based analysis.
Nice To Haves
- Experience or familiarity with mass spectrometry.
- Familiarity with RNA characterization techniques such as SEC, CE, RT-PCR, or RNAseq.
- Experience with LIMS and Benchling.
Responsibilities
- Perform routine analytical assays, including ELISA, HPLC, and other analytical methods, supporting research, process development, stability, and quality control activities.
- Execute and document laboratory experiments according to established SOPs, protocols, and GLP standards.
- Analyze, interpret, and summarize experimental data, and prepare clear laboratory reports and technical summaries.
- Maintain laboratory equipment, including calibration and troubleshooting, and coordinate preventive maintenance with vendors.
- Prepare reagents, buffers, and standards for analytical testing, and manage laboratory consumables and supplies inventory.
- Support method development and optimization under the guidance of senior scientists.
- Comply with safety regulations, EHS guidelines, and company policies.
- Collaborate with colleagues in research, process development, and formulations as part of cross-functional teams.
- Present results to the team and larger research community.
Benefits
- May be eligible for additional discretionary incentive cash and stock opportunities.
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What This Job Offers
Job Type
Full-time
Career Level
Senior
