About The Position

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept. Position Summary We are seeking a Senior Associate Scientist with strong in vivo skills, experience with standard molecular biology/biochemical assays, and a strong interest/background in neuroscience to join our in vivo pharmacology group. As part of the Neuroscience Thematic Research Center (TRC), we support portfolio programs, discovery projects, and platform development across multiple neurological disease indications and therapeutic modalities, including a particular focus on the delivery of oligonucleotide therapeutics across the blood-brain barrier. This is a highly collaborative role, with the opportunity to work across the Neuroscience TRC and with other functions at BMS.

Requirements

  • Bachelor’s Degree 4+ years of academic and / or industry experience
  • Or Master’s Degree 2+ years of academic and / or industry experience

Nice To Haves

  • Bachelor’s Degree in Neuroscience, Biology, or related field and 2+ years of academic and/or industry experience or Master’s Degree in Neuroscience, Biology, or related field
  • Extensive mouse handling experience, including common dosing routes, and tissue collection from CNS and peripheral tissues required
  • Proficiency in standard molecular biology or biochemical assays required
  • Background in mouse genetics and/or neuroanatomy required
  • Experience with rodent stereotaxic surgery
  • Familiarity with in vivo bioluminescence imaging
  • Experience with mouse breeding or colony management
  • Immunohistochemistry techniques
  • Experience working with contract research organization (CROs)
  • Strong organizational and communication skills
  • Ability to work independently and as part of a team
  • Detail-oriented with a commitment to scientific rigor and reproducibility
  • Adaptability in a fast-paced, collaborative research environment

Responsibilities

  • Performing in vivo pharmacology studies in mice, inclusive of in-life dosing (IV, SC, IP, PO), tissue collection, and tissue processing
  • Performing and/or supporting stereotaxic surgery in mice
  • Performing and analyzing PK/PD readouts, such as ELISA, LC-MS, ddPCR, and Western blot

Benefits

  • Health Coverage: Medical, pharmacy, dental, and vision care.
  • Wellbeing Support: Programs such as BMS Well-Being Account, BMS Living Life Better, and Employee Assistance Programs (EAP).
  • Financial Well-being and Protection: 401(k) plan, short- and long-term disability, life insurance, accident insurance, supplemental health insurance, business travel protection, personal liability protection, identity theft benefit, legal support, and survivor support.
  • Work-life benefits include: Paid Time Off US Exempt Employees: flexible time off (unlimited, with manager approval, 11 paid national holidays (not applicable to employees in Phoenix, AZ, Puerto Rico or Rayzebio employees) Phoenix, AZ, Puerto Rico and Rayzebio Exempt, Non-Exempt, Hourly Employees: 160 hours annual paid vacation for new hires with manager approval, 11 national holidays, and 3 optional holidays Based on eligibility, additional time off for employees may include unlimited paid sick time, up to 2 paid volunteer days per year, summer hours flexibility, leaves of absence for medical, personal, parental, caregiver, bereavement, and military needs and an annual Global Shutdown between Christmas and New Years Day. All global employees full and part-time who are actively employed at and paid directly by BMS at the end of the calendar year are eligible to take advantage of the Global Shutdown.
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